疫苗试验中的新伦理考量。
New ethical considerations in vaccine trials.
机构信息
a Liverpool School of Tropical Medicine , Liverpool , UK.
出版信息
Hum Vaccin Immunother. 2017 Sep 2;13(9):2160-2163. doi: 10.1080/21645515.2016.1272744. Epub 2017 Jan 25.
Abstract
Known and novel pathogens continue to afflict the world's population, and we deploy existing and new vaccines - the best type of weapon we've got - against them. One consequence is that we are accumulating steadily more experience of both the scientific and the ethical requirements of conducting vaccine trials in people. Good science is itself an ethical requirement, as it is meaningless to apply ethical principles to a scientifically flawed product or plan. Bad science can only be bad ethics. And we have learned that ethical principles are a necessity when we apply the benefits of science to the improving of human health. Recent epidemics have provided opportunities to expand our understanding of this field and of the many components of it that we recognize to be necessary to the ethical assessment of vaccines.
摘要
已知和新型病原体继续困扰着世界人口，我们使用现有的和新的疫苗——这是我们拥有的最佳武器——来对抗它们。其结果是，我们在人群中进行疫苗试验的科学和伦理要求方面的经验不断积累。良好的科学本身就是伦理要求，因为将伦理原则应用于科学有缺陷的产品或计划是没有意义的。不良的科学只能是不良的伦理。而且，当我们将科学的益处应用于改善人类健康时，我们已经了解到伦理原则是必要的。最近的流行病为我们提供了机会，扩大了我们对这一领域以及我们认识到对疫苗伦理评估必不可少的许多组成部分的理解。
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