Renoult E, Cochat P, Jonon B, Kessler M
Hôpital de Brabois, Service de néphrologie, Vandoeuvre-lès-Nancy, France.
Pediatrie. 1989;44(5):365-74.
Primary IgA mesangial nephropathy was first described in adults by Berger, and has been increasingly recognized in children. IgA nephropathy is a frequent type of glomerulonephritis in 3 to 15 year-old children in France. Clinical features and outcome have been defined and the progression to renal failure is possible. The pathogeny of IgA nephropathy remains unclear and is under multifactorial control and, at present, no satisfactory specific treatment is available.
原发性IgA系膜肾病最早由伯杰在成人中描述，目前在儿童中也越来越受到关注。IgA肾病是法国3至15岁儿童中常见的一种肾小球肾炎类型。其临床特征和预后已得到明确，且有可能进展为肾衰竭。IgA肾病的发病机制仍不清楚，受多种因素控制，目前尚无令人满意的特异性治疗方法。
