Ueshima Shigeyuki, Oka Yoshio, Hayashida Hiroto, Higaki Yoshizumi, Yoshioka Shinichi, Okada Kaoru, Nezu Riichiro
Dept. of Surgery, Nishinomiya Municipal Central Hospital.
Gan To Kagaku Ryoho. 2016 Nov;43(12):1653-1655.
Pancreatic neuroendocrine tumor(P-NET)often involve liver metastases. We report a 52-year-old woman who underwent distal pancreatectomy for a pancreatic body tumor with a diameter of 8 cm. The pathological findings were P-NETG2 . After 1 year 6 months, a liver metastasis was detected. We performed partial hepatectomy. The pathological findings showed a Ki-67 index of 23%. After surgery, CPT-11 plus CDDP therapy and AMR therapy were administered.
Multimodal therapies should be considered for P-NETliver metastases based on the Ki-67 index.
胰腺神经内分泌肿瘤(P-NET)常发生肝转移。我们报告一名52岁女性,因胰体部直径8 cm的肿瘤接受了胰腺远端切除术。病理结果为P-NET G2。1年6个月后,检测到肝转移。我们进行了肝部分切除术。病理结果显示Ki-67指数为23%。术后给予CPT-11联合顺铂治疗及AMR治疗。
对于P-NET肝转移,应根据Ki-67指数考虑多模式治疗。