Tokuyama Shinji, Yoshioka Shinichi, Fukunaga Mutsumi, Honda Shoko, Yukimoto Ryohei, Okamoto Aoi, Saito Akina, Konishi Ken, Okada Kazuyuki, Ota Hideo, Yokoyama Kazusige, Miki Hirofumi, Kobayashi Kenji
Dept. of Digestive Surgery, Hyogo Prefectural Nishinomiya Hospital.
Gan To Kagaku Ryoho. 2016 Nov;43(12):2459-2461.
Pancreatic metastasis of colorectal cancer is uncommon and is often identified in later stages of cancer, thereby making resection more uncommon. We report a case oflong -term survival after resection of metachronous metastasis to the pancreas from primary sigmoid colon cancer. A 50-year-old female patient underwent a sigmoid colon resection and bilateral salpingo-oophorectomy for sigmoid colon cancer and metastatic ovarian cancer in 2007. She underwent partial lung resection for metastatic lung cancer twice. Four years and 11 months after the first operation, an isolated mass was identified in the pancreatic tail, and a distal pancreatectomy, splenectomy, left adrenal gland removal, and regional lymph node dissection were performed. The tumor stained negatively for cytokeratin 7 and positively for cytokeratin 20, resulting in a diagnosis of pancreatic metastatic cancer from sigmoid colon cancer. The patient is alive 3 years and 4 months after distal pancreatectomy. This suggests that curative resection is effective for metastasis of colorectal cancer to the pancreas, similarly to metastases to the liver and lung.
结直肠癌的胰腺转移并不常见,且常在癌症晚期才被发现,因此手术切除更为罕见。我们报告一例原发性乙状结肠癌发生异时性胰腺转移后行手术切除并长期存活的病例。一名50岁女性患者于2007年因乙状结肠癌和转移性卵巢癌接受了乙状结肠切除术及双侧输卵管卵巢切除术。她因转移性肺癌接受了两次部分肺切除术。首次手术后四年零十一个月,在胰尾部发现一个孤立肿块,遂行胰体尾切除术、脾切除术、左肾上腺切除术及区域淋巴结清扫术。肿瘤细胞角蛋白7染色阴性,细胞角蛋白20染色阳性,诊断为乙状结肠癌胰腺转移癌。患者在胰体尾切除术后3年零4个月仍存活。这表明,与结直肠癌肝转移和肺转移一样,根治性切除对结直肠癌胰腺转移有效。