联合磁场疗法在骨折不愈合治疗中的应用。
Use of Combined Magnetic Field Treatment for Fracture Nonunion.
作者信息
Phillips Mark, Baumhauer Judy, Sprague Sheila, Zoltan Jon
机构信息
Global Research Solutions, Inc., Burlington, Ontario, Canada.
University of Rochester Medical Center, Orthopaedics Department, Rochester, NY.
出版信息
J Long Term Eff Med Implants. 2016;26(3):277-284. doi: 10.1615/JLongTermEffMedImplants.2016016818.
The use of noninvasive bone growth stimulators is a nonoperative treatment option for fracture nonunions. The purpose of this study was to evaluate the initial effectiveness of the combined magnetic field (CMF) bone growth stimulation in the treatment of fracture nonunions. Using data from a large nonunion fracture registry, we reviewed fracture-healing-outcome data and healing times for all patients treated with a CMF bone growth stimulator during a 4-yr period. Overall, 75% of the 2370 included patients achieved fracture union. Healing rates ranged from 64.0% in patients with femoral fractures to 89.7% in patients with carpal/metacarpal fractures. The weighted mean time to heal was 4.9 ± 1.0 mo. Patients treated earlier than 6 mo with CMF following injury demonstrated significantly greater healing rates and shorter mean times to heal than patients treated 6 mo or more following injury. These results indicate that CMF bone stimulation is a potentially beneficial noninvasive treatment modality for nonunions; however, high-quality comparative research is required to further evaluate the efficacy, potential prognostic factors, and contraindications for the use of this treatment modality.
使用非侵入性骨生长刺激器是骨折不愈合的一种非手术治疗选择。本研究的目的是评估联合磁场(CMF)骨生长刺激在治疗骨折不愈合中的初始有效性。利用来自大型骨折不愈合登记处的数据,我们回顾了在4年期间接受CMF骨生长刺激器治疗的所有患者的骨折愈合结果数据和愈合时间。总体而言,纳入的2370例患者中有75%实现了骨折愈合。愈合率从股骨骨折患者的64.0%到腕骨/掌骨骨折患者的89.7%不等。加权平均愈合时间为4.9±1.0个月。受伤后6个月内接受CMF治疗的患者比受伤6个月或更长时间后接受治疗的患者表现出明显更高的愈合率和更短的平均愈合时间。这些结果表明,CMF骨刺激是一种对骨折不愈合可能有益的非侵入性治疗方式;然而,需要高质量的比较研究来进一步评估这种治疗方式的疗效、潜在的预后因素和禁忌症。