Rajamani Muralidhar, Nagasubramanian Vidhya, Ayyavoo Ahila, Raghupathy Palany, Dandapani Ramamurthy
b Department of Pediatric Ophthalmology and Strabismus , The Eye Foundation , Coimbatore , India.
a Department of Paediatric Endocrinology and Diabetes , G. Kuppuswamy Naidu Memorial Hospital , Coimbatore , India.
Strabismus. 2017 Mar;25(1):39-42. doi: 10.1080/09273972.2016.1277768. Epub 2017 Jan 31.
Surgically induced necrotizing scleritis (SINS) is a rare but serious disorder that can develop many years after strabismus surgery. It is generally treated with high-dose steroids or immunosuppression.
We describe a patient with Varadi Papp syndrome and congenital fibrosis of the extraocular muscles, who developed surgically induced necrotizing scleritis a month after strabismus surgery and was successfully managed by oral vitamin C and topical N-acetylcysteine 10%.
While SINS is conventionally treated with steroids/immunosuppression, a conservative approach may be tried in milder cases. The role of topical N-acetylcysteine in managing this complication needs to be explored.
手术诱发的坏死性巩膜炎(SINS)是一种罕见但严重的疾病,可在斜视手术后数年发生。通常采用大剂量类固醇或免疫抑制治疗。
我们描述了一名患有瓦拉迪 - 帕普综合征和眼外肌先天性纤维化的患者,该患者在斜视手术后一个月发生了手术诱发的坏死性巩膜炎,并通过口服维生素C和局部使用10%的N - 乙酰半胱氨酸成功治疗。
虽然传统上SINS采用类固醇/免疫抑制治疗,但在较轻的病例中可尝试保守方法。局部使用N - 乙酰半胱氨酸在处理这种并发症中的作用需要进一步探索。