低血糖恐惧：对1型糖尿病青年患者血糖变异性及自我管理行为的影响
Fear of hypoglycemia: Influence on glycemic variability and self-management behavior in young adults with type 1 diabetes.
作者信息
Martyn-Nemeth Pamela, Quinn Laurie, Penckofer Sue, Park Chang, Hofer Vanessa, Burke Larisa
机构信息
University of Illinois at Chicago, College of Nursing, Chicago, IL.
University of Illinois at Chicago, College of Nursing, Chicago, IL.
出版信息
J Diabetes Complications. 2017 Apr;31(4):735-741. doi: 10.1016/j.jdiacomp.2016.12.015. Epub 2017 Jan 20.
PURPOSE
The purpose of this study was to examine how fear of hypoglycemia (FOH) is associated with glycemic variability (GV) and self-management behavior in young adults (aged 18-35) with type 1 diabetes (T1DM).
PROCEDURES
Using a prospective repeated-measures design, in 35 young adults, within- and between-person and temporal associations of FOH, specific self-management behaviors, and GV were measured. The data were collected using questionnaires and real-time measures using daily diaries, insulin pump downloads, actigraphy, and continuous glucose monitoring.
FINDINGS
FOH was associated with greater glycemic variability. Significant temporal associations emerged. Concurrent day (glucose SD, p=.011) and previous-evening fear levels were associated with GV (glucose SD, p=.007). FOH was also associated with greater calorie intake (r=.492, p=.003) and less physical activity (light activity, r=-.341, p=.045).
CONCLUSIONS
The significant associations of FOH with GV, dietary patterns, and physical activity provide evidence for FOH as an important psychological factor associated with diabetes care.
目的
本研究旨在探讨低血糖恐惧（FOH）与1型糖尿病（T1DM）青年成年人（18 - 35岁）的血糖变异性（GV）及自我管理行为之间的关联。
程序
采用前瞻性重复测量设计，对35名青年成年人测量了FOH、特定自我管理行为和GV的个体内、个体间及时间关联。数据通过问卷调查以及使用日常日记、胰岛素泵下载数据、活动记录仪和连续血糖监测进行实时测量来收集。
结果
FOH与更大的血糖变异性相关。出现了显著的时间关联。当日（血糖标准差，p = 0.011）和前一晚的恐惧水平与GV相关（血糖标准差，p = 0.007）。FOH还与更高的热量摄入（r = 0.492，p = 0.003）和更少的身体活动（轻度活动，r = - 0.341，p = 0.045）相关。
结论
FOH与GV、饮食模式和身体活动之间的显著关联为FOH作为与糖尿病护理相关的重要心理因素提供了证据。
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