Liu Yuanqi, Gao Yang, Zhang Huajun, Cheng Yuanda, Chang Ruimin, Zhang Weixing, Zhang Chunfang
Department of Thoracic Surgery, Xiangya Hospital Central South University, Changsha 410000, China.
J Thorac Dis. 2016 Dec;8(12):3537-3542. doi: 10.21037/jtd.2016.12.24.
Pneumonectomy is a proven treatment for lung diseases. We sought to present a comparison between video-assisted thoracic surgery pneumonectomy (VATS-P) and conventional thoracotomy pneumonectomy (CP) on perioperative outcomes and short-term measures of convalescence.
A retrospective cohort study was performed to assess perioperative outcomes among patients underwent VATS-P and CP. A total of 32 patients undergoing VATS-P were matched 2:1 about comorbidity, surgical indication, tumour size and lesion location to a previous cohort of 64 patients who underwent CP. Demographic and perioperative data were obtained. Statistical analysis was performed.
Mean patient age was 55.4 years for both groups, with equal sex distribution. Pneumonectomy for malignant and benign lesion patients was evaluated individually. For malignant tumour patients, median tumour size was 3.9 cm for both groups. There was no difference between VATS-P and CP cases in transfusion rates (2% 10%, P=0.50), dissected lymph node numbers (11.9 14.2, P=0.26), dissected lymph node stations (5.0 4.9, P=0.75), estimated blood loss (226.0 261.3 mL, P=0.40), complication rate (20.0% 22.5%, P=0.82), postoperative drainage time (5.9 6.2, P=0.50) or length of hospital stay (7.5 8.1, P=0.50). Operation time in VATS-P was higher than conventional groups (187.5 146.3 min, P=0.00) but the mean pain score was significantly less. For benign patients, over 1,000 mL blood losing (1,033.3 1,233.3 mL, P=0.78) and 180 minutes (186.6 105.8, P=0.73) OR time was found in both groups. The Length of stay (7.6 6.3 d, P=0.57), transfusion rates (66.7% 33.3%), complications rates (zero in both group) and length of drainage (6.7 6.7 d, P=1.0) between two groups are identical.
Complete video-assisted thoracic surgery (VATS) pneumonectomy is feasible and safe technique and can be recommended as a surgical treatment for lung cancer patients. However, long-term benefits need to be evaluated by further studies and large sample tests.
肺切除术是治疗肺部疾病的一种成熟方法。我们试图比较电视辅助胸腔镜肺切除术(VATS-P)和传统开胸肺切除术(CP)的围手术期结果及短期康复指标。
进行一项回顾性队列研究,以评估接受VATS-P和CP的患者的围手术期结果。总共32例接受VATS-P的患者在合并症、手术指征、肿瘤大小和病变位置方面按2:1与先前一组64例接受CP的患者进行匹配。获取人口统计学和围手术期数据并进行统计分析。
两组患者的平均年龄均为55.4岁,性别分布均衡。分别对恶性和良性病变患者的肺切除术进行评估。对于恶性肿瘤患者,两组的肿瘤中位大小均为3.9 cm。VATS-P组和CP组在输血率(2%对10%,P = 0.50)、清扫淋巴结数量(11.9对14.2,P = 0.26)、清扫淋巴结站数(5.0对4.9,P = 0.75)、估计失血量(226.0对261.3 mL,P = 0.40)、并发症发生率(20.0%对22.5%,P = 0.82)、术后引流时间(5.9对6.2,P = 0.50)或住院时间(7.5对8.1,P = 0.50)方面无差异。VATS-P组的手术时间高于传统组(187.5对146.3分钟,P = 0.00),但平均疼痛评分明显更低。对于良性患者,两组均出现超过1000 mL失血(1033.3对1233.3 mL,P = 0.78)和180分钟(186.6对105.8,P = 0.73)的手术时间。两组之间的住院时间(7.6对6.3天,P = 0.57)、输血率(66.7%对33.3%)、并发症发生率(两组均为零)和引流时间(6.7对6.7天,P = 1.0)相同。
完全电视辅助胸腔镜(VATS)肺切除术是一种可行且安全的技术,可推荐作为肺癌患者的手术治疗方法。然而,长期益处需要通过进一步研究和大样本试验来评估。