Welches C D, Scavelli T D, Matthiesen D T, Peterson M E
Department of Surgery, Animal Medical Center, New York, NY 10021.
Vet Surg. 1989 Sep-Oct;18(5):392-6. doi: 10.1111/j.1532-950x.1989.tb01107.x.
Bilateral thyroidectomy was performed in 106 cats with hyperthyroidism by one of three techniques: original intracapsular, modified intracapsular, or modified extracapsular. Hypocalcemia was detected in the first 3 days after surgery in 11 (22%) of 50 cats treated by the intracapsular technique, 10 (33%) of 30 cats treated by the modified intracapsular technique, and 6 (23%) of 26 cats treated by the modified extracapsular technique. Hypocalcemia was classified as mild or severe. No signs of hypoparathyroidism developed in any of the 13 cats with mild hypocalcemia. Of the 14 cats with severe hypocalcemia, 8 had clinical signs of hypoparathyroidism before and during treatment with calcium and vitamin D, 3 were treated and no clinical signs developed, 2 were not treated but no clinical signs developed, and 1 was lost to follow-up. No cat required permanent calcium or vitamin D supplementation after surgery. Severe hypocalcemia and clinical signs of hypoparathyroidism occurred in 3 (6%) of the 50 cats treated by the intracapsular technique, 4 (13.3%) of the 30 cats treated by the modified intracapsular technique, and 1 (3.8%) of the 26 cats treated by the modified extracapsular technique. Twelve cats had recurrence of hyperthyroidism at a median time of 23 months. The intracapsular technique was used in 11 of these cats, and the modified extracapsular technique was used in 1. No clinical signs of hypothyroidism were detected in any of the cats. The modified intracapsular and modified extracapsular techniques of bilateral thyroidectomy are effective procedures for the treatment of feline hyperthyroidism.
采用三种技术之一对106只患有甲状腺功能亢进的猫实施双侧甲状腺切除术:原始囊内切除术、改良囊内切除术或改良囊外切除术。采用囊内技术治疗的50只猫中,有11只(22%)在术后前3天检测到低钙血症;采用改良囊内技术治疗的30只猫中,有10只(33%)出现低钙血症;采用改良囊外技术治疗的26只猫中,有6只(23%)出现低钙血症。低钙血症分为轻度或重度。13只轻度低钙血症的猫均未出现甲状旁腺功能减退的迹象。14只重度低钙血症的猫中,8只在补钙和补充维生素D治疗前及治疗期间有甲状旁腺功能减退的临床症状,3只接受治疗后未出现临床症状,2只未接受治疗但也未出现临床症状,1只失访。术后没有猫需要长期补充钙或维生素D。采用囊内技术治疗的50只猫中,有3只(6%)出现重度低钙血症和甲状旁腺功能减退的临床症状;采用改良囊内技术治疗的30只猫中,有4只(13.3%)出现上述情况;采用改良囊外技术治疗的26只猫中,有1只(3.8%)出现上述情况。12只猫出现甲状腺功能亢进复发,中位复发时间为23个月。其中11只猫采用了囊内技术,1只采用了改良囊外技术。所有猫均未检测到甲状腺功能减退的临床症状。双侧甲状腺切除术的改良囊内和改良囊外技术是治疗猫甲状腺功能亢进的有效方法。