艰难梭菌感染联合治疗无获益
Lack of Benefit With Combination Therapy for Clostridium difficile Infection.
作者信息
Njoku Jessica C, Van Schooneveld Trevor C, Rupp Mark E, Olsen Keith M, Qiu Fang, Meza Jane L, Hermsen Elizabeth D
机构信息
1Nebraska Medicine,Omaha,Nebraska.
4Department of Biostatistics,University of Nebraska Medical Center,Omaha,Nebraska.
出版信息
Infect Control Hosp Epidemiol. 2017 May;38(5):602-605. doi: 10.1017/ice.2016.320. Epub 2017 Feb 6.
Limited data exist regarding combination therapy for Clostridium difficile infection (CDI). After adjusting for confounders in a cohort of patients with CDI and≥1 year old, combination therapy was not associated with significant differences in clinical outcomes, but it was associated with prolonged duration of therapy (1.22 days; 95% confidence interval, 1.03-1.44 days; P=.02). Infect Control Hosp Epidemiol 2017;38:602-605.
关于艰难梭菌感染（CDI）联合治疗的数据有限。在对一组年龄≥1岁的CDI患者的混杂因素进行调整后，联合治疗与临床结局的显著差异无关，但与治疗时间延长有关（1.22天；95%置信区间，1.03 - 1.44天；P = 0.02）。《感染控制与医院流行病学》2017年；38:602 - 605。
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