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手术重症监护患者中静脉注射氟哌啶醇治疗急性非特异性谵妄

Treatment of acute nonspecific delirium with i.v. haloperidol in surgical intensive care patients.

作者信息

Moulaert P

出版信息

Acta Anaesthesiol Belg. 1989;40(3):183-6.

PMID:2816247
Abstract

Acute delirium may be treated by the alleviation of pain, by the restoration of specific physiological equilibria (by means of oxygen, glucose, vitamins, etc.) or by discontinuing psychotogenic medication. Acute nonspecific delirium can be treated with a specific psychopharmacological agent. Six surgical intensive care patients with acute nonspecific delirium were treated effectively with intravenous haloperidol. A dose of 38 +/- 17 (mean +/- SEM) mg was needed to calm them. Respiratory rate, heart rate and systolic-diastolic arterial blood pressure all significantly decreased returning to normal values. No side effects were recorded.

摘要

急性谵妄可通过缓解疼痛、恢复特定生理平衡(借助氧气、葡萄糖、维生素等)或停用致精神障碍药物来治疗。急性非特异性谵妄可用特定的精神药物治疗。六名患有急性非特异性谵妄的外科重症监护患者经静脉注射氟哌啶醇后得到有效治疗。使他们镇静需要38±17(均值±标准误)毫克的剂量。呼吸频率、心率和动脉收缩压与舒张压均显著下降并恢复到正常值。未记录到副作用。

相似文献

1
Treatment of acute nonspecific delirium with i.v. haloperidol in surgical intensive care patients.手术重症监护患者中静脉注射氟哌啶醇治疗急性非特异性谵妄
Acta Anaesthesiol Belg. 1989;40(3):183-6.
2
Treatment of severe, refractory agitation with a haloperidol drip.用氟哌啶醇静脉滴注治疗严重的难治性激越。
J Clin Psychiatry. 1988 Jun;49(6):239-41.
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Morphine is a reasonable alternative to haloperidol in the treatment of postoperative hyperactive-type delirium after cardiac surgery.吗啡是心脏手术后治疗高动力型术后谵妄的一种合理的氟哌啶醇替代药物。
J Cardiothorac Vasc Anesth. 2013 Oct;27(5):933-8. doi: 10.1053/j.jvca.2013.01.017. Epub 2013 Jun 18.
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Prolongation of the corrected QT and torsades de pointes cardiac arrhythmia associated with intravenous haloperidol in the medically ill.患有内科疾病的患者静脉注射氟哌啶醇后出现校正QT间期延长及尖端扭转型室性心律失常。
J Clin Psychopharmacol. 1993 Apr;13(2):128-32.
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Use of haloperidol infusions to control delirium in critically ill adults.使用氟哌啶醇静脉输注来控制重症成年患者的谵妄。
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引用本文的文献

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Haloperidol dosing strategies in the treatment of delirium in the critically ill.氟哌啶醇在危重症患者谵妄治疗中的剂量策略。
Neurocrit Care. 2012 Feb;16(1):170-83. doi: 10.1007/s12028-011-9643-3.
2
Usage of haloperidol for delirium in cancer patients.氟哌啶醇在癌症患者谵妄中的应用。
Support Care Cancer. 1996 Sep;4(5):390-2. doi: 10.1007/BF01788847.