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手术重症监护患者中静脉注射氟哌啶醇治疗急性非特异性谵妄

Treatment of acute nonspecific delirium with i.v. haloperidol in surgical intensive care patients.

作者信息

Moulaert P

出版信息

Acta Anaesthesiol Belg. 1989;40(3):183-6.

PMID:2816247
Abstract

Acute delirium may be treated by the alleviation of pain, by the restoration of specific physiological equilibria (by means of oxygen, glucose, vitamins, etc.) or by discontinuing psychotogenic medication. Acute nonspecific delirium can be treated with a specific psychopharmacological agent. Six surgical intensive care patients with acute nonspecific delirium were treated effectively with intravenous haloperidol. A dose of 38 +/- 17 (mean +/- SEM) mg was needed to calm them. Respiratory rate, heart rate and systolic-diastolic arterial blood pressure all significantly decreased returning to normal values. No side effects were recorded.

摘要

急性谵妄可通过缓解疼痛、恢复特定生理平衡(借助氧气、葡萄糖、维生素等)或停用致精神障碍药物来治疗。急性非特异性谵妄可用特定的精神药物治疗。六名患有急性非特异性谵妄的外科重症监护患者经静脉注射氟哌啶醇后得到有效治疗。使他们镇静需要38±17(均值±标准误)毫克的剂量。呼吸频率、心率和动脉收缩压与舒张压均显著下降并恢复到正常值。未记录到副作用。

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