Rosenberg Stephen A, Baschnagel Andrew M, Bagley Stephen J, Housri Nadine
Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53792, USA.
Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, 3400 Civic Center Blvd, Perelman Center South Pavilion Extension, 10th Floor, Room 134, Philadelphia, PA, 19104, USA.
Curr Oncol Rep. 2017 Jan;19(1):5. doi: 10.1007/s11912-017-0563-z.
The landscape of non-small cell lung cancer (NSCLC) treatment has rapidly evolved over the past decade. This is exemplified by the use of molecular targeted agents, immunotherapies, and newer technologies such as stereotactic body radiotherapy (SBRT). As the translation of preclinical discoveries into clinical practice continues, the effective dissemination and implementation of evidence-based treatment of NSCLC will remain a foremost challenge for oncologists. To further extend evidence-based medicine into the community setting, community oncologists are being engaged on multiple fronts including leadership and participation in national clinical trials and utilization of internet-based resources.
在过去十年中,非小细胞肺癌(NSCLC)的治疗格局迅速演变。分子靶向药物、免疫疗法以及立体定向体部放疗(SBRT)等新技术的应用便是例证。随着临床前研究成果不断转化为临床实践,有效传播和实施基于证据的NSCLC治疗方案,仍将是肿瘤学家面临的首要挑战。为了将循证医学进一步拓展到社区医疗环境中,社区肿瘤学家正从多个方面积极参与,包括在国家临床试验中发挥领导作用并参与其中,以及利用基于互联网的资源。