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小儿原发性自发性气胸的胸膜切除术与胸膜摩擦术对比研究

Pleurectomy versus pleural abrasion for primary spontaneous pneumothorax in children.

作者信息

Joharifard Shahrzad, Coakley Brian A, Butterworth Sonia A

机构信息

Division of General Surgery, Department of Surgery, University of British Columbia, Vancouver, Canada.

Division of Pediatric Surgery, Department of Surgery, British Columbia Children's Hospital, University of British Columbia, Vancouver, Canada.

出版信息

J Pediatr Surg. 2017 May;52(5):680-683. doi: 10.1016/j.jpedsurg.2017.01.012. Epub 2017 Jan 27.

Abstract

PURPOSE

Primary spontaneous pneumothorax (PSP) represents a common indication for urgent surgical intervention in children. First episodes are often managed with thoracostomy tube, whereas recurrent episodes typically prompt surgery involving apical bleb resection and pleurodesis, either via pleurectomy or pleural abrasion. The purpose of this study was to assess whether pleurectomy or pleural abrasion was associated with lower postoperative recurrence.

METHODS

The records of patients undergoing surgery for PSP between February 2005 and December 2015 were retrospectively reviewed. Recurrence was defined as an ipsilateral pneumothorax requiring surgical intervention. Bivariate logistic regressions were used to identify factors associated with recurrence.

RESULTS

Fifty-two patients underwent 64 index operations for PSP (12 patients had surgery for contralateral pneumothorax, and each instance was analyzed separately). The mean age was 15.7±1.2years, and 79.7% (n=51) of patients were male. In addition to apical wedge resection, 53.1% (n=34) of patients underwent pleurectomy, 39.1% (n=25) underwent pleural abrasion, and 7.8% (n=5) had no pleural treatment. The overall recurrence rate was 23.4% (n=15). Recurrence was significantly lower in patients who underwent pleurectomy rather than pleural abrasion (8.8% vs. 40%, p<0.01). In patients who underwent pleural abrasion without pleurectomy, the relative risk of recurrence was 2.36 [1.41-3.92, p<0.01].

CONCLUSION

Recurrence of PSP is significantly reduced in patients undergoing pleurectomy compared to pleural abrasion.

LEVEL OF EVIDENCE

Level III, retrospective comparative therapeutic study.

摘要

目的

原发性自发性气胸(PSP)是儿童紧急外科手术干预的常见指征。首次发作通常采用胸腔闭式引流管治疗,而复发性发作通常促使进行手术,包括通过胸膜切除术或胸膜摩擦术切除肺尖部肺大疱并进行胸膜固定术。本研究的目的是评估胸膜切除术或胸膜摩擦术是否与较低的术后复发率相关。

方法

回顾性分析2005年2月至2015年12月期间接受PSP手术患者的记录。复发定义为需要手术干预的同侧气胸。采用双变量逻辑回归分析确定与复发相关的因素。

结果

52例患者接受了64例PSP初次手术(12例患者因对侧气胸接受手术,每个病例单独分析)。平均年龄为15.7±1.2岁,79.7%(n=51)的患者为男性。除肺尖楔形切除外,53.1%(n=34)的患者接受了胸膜切除术,39.1%(n=25)的患者接受了胸膜摩擦术,7.8%(n=5)的患者未进行胸膜治疗。总体复发率为23.4%(n=15)。接受胸膜切除术的患者复发率明显低于接受胸膜摩擦术的患者(8.8%对40%,p<0.01)。在未进行胸膜切除术而仅接受胸膜摩擦术的患者中,复发的相对风险为2.36[1.41-3.92,p<0.01]。

结论

与胸膜摩擦术相比,接受胸膜切除术的PSP患者复发率显著降低。

证据水平

三级,回顾性比较治疗研究。

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