Marotti Maja, Ebeleseder Kurt Alois, Schwantzer Gerold, Jauk Stefanie
Division of Preventive and Operative Dentistry, Endodontics, Pedodontics and Minimally Invasive Dentistry, University Clinic for Dental Medicine and Oral Health, Medical University of Graz, Graz, Austria.
Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
Dent Traumatol. 2017 Jun;33(3):165-174. doi: 10.1111/edt.12325. Epub 2017 Apr 5.
BACKGROUND/AIM: There is a lack of studies of fractures of the alveolar process (FAP). Only five were published in the last 50 years. The aim of this study was to analyze the risk of pulp necrosis and infection (PN), pulp canal obliteration (PCO), infection-related root resorption (IRR), ankylosis-related resorption (ARR), marginal bone loss (MBL), and tooth loss (TL) as well as to identify the possible risk factors for teeth involved in an isolated alveolar process fracture. In the second part, any late complications of the involved teeth were reported in patients who responded to a follow-up examination.
This study was a retrospective analysis of 126 patients with 329 traumatized permanent teeth treated in a regional dental trauma clinic. Follow-up examination was performed on 31 (24.6%) patients with 75 (22.8%) teeth. The risks of PN, PCO, RR, MBL, and TL were analyzed using the Kaplan-Meier method. Possible risk factors for PN (stage of root development, fracture position in relation to the root apex, concomitant injury, treatment delay, and antibiotics) were analyzed using univariate and multivariate Cox regression and generalized estimating equation. The level of significance was 5%.
Pulp necrosis was observed in 43% of the teeth, and it was significantly associated with the presence of a concomitant injury and complete root formation. PCO was recorded in 2.8%, root resorption (RR, IRR, and ARR) in 4%, MBL in 8%, and TL in 0.6% of the teeth. Thirty-four percent of the teeth were assumed to have normal pulps, but they did not respond to pulp sensibility testing. At the follow-up examination, PN was found in 49%, PCO in 28%, RR (IRR and ARR) in 4%, MBL in 17%, and TL in 5%. Estimated risk after a 5-years follow up was as follows: PN: 48.2% (95% confidence interval (CI): 42.0-54.5), IRR: 7.2 (95% CI: 3.5-10.9), ARR: 33.0% (95% CI: 22.4-43.6), BL: 16.7% (95% CI: 9.6-23.8), TL: 4.0% (95% CI: 0.0-8.5). The following factors significantly increased the risk of PN: mature root development (hazard ratio [HR]: 7.50 [95% CI: 1.84-30.64], P=.005) and concomitant injury (HR: 2.68 [95% CI: 1.76-4.09], P<.001). In a logistic regression model, teeth with mature roots had a threefold risk of becoming non-responsive to pulp testing.
Teeth involved in an isolated alveolar process fracture and managed with a conservative treatment approach appear to have a good prognosis. The most common complication was PN which did not negatively affect the survival of the teeth after root canal treatment.
背景/目的:关于牙槽突骨折(FAP)的研究较少。在过去50年中仅发表了5篇相关研究。本研究旨在分析牙髓坏死与感染(PN)、根管闭锁(PCO)、感染相关的牙根吸收(IRR)、粘连相关的吸收(ARR)、边缘性骨吸收(MBL)和牙齿脱落(TL)的风险,并确定孤立性牙槽突骨折累及牙齿的可能危险因素。在第二部分中,报告了接受随访检查患者中受累牙齿的任何晚期并发症。
本研究是对一家地区性牙外伤诊所治疗的126例患者的329颗外伤恒牙进行的回顾性分析。对31例(24.6%)患者的75颗(22.8%)牙齿进行了随访检查。采用Kaplan-Meier方法分析PN、PCO、RR、MBL和TL的风险。使用单因素和多因素Cox回归以及广义估计方程分析PN的可能危险因素(牙根发育阶段、骨折相对于根尖的位置、合并损伤、治疗延迟和抗生素)。显著性水平为5%。
43%的牙齿出现牙髓坏死,且与合并损伤和牙根完全形成显著相关。2.8%的牙齿记录有PCO,4%的牙齿有牙根吸收(RR、IRR和ARR),8%的牙齿有MBL,0.6%的牙齿有TL。34%的牙齿被认为牙髓正常,但对牙髓敏感性测试无反应。在随访检查中,发现49%的牙齿有PN,28%的牙齿有PCO,4%的牙齿有RR(IRR和ARR),17%的牙齿有MBL,5%的牙齿有TL。5年随访后的估计风险如下:PN:48.2%(95%置信区间(CI):42.0 - 54.5),IRR:7.2(95%CI:3.5 - 10.9),ARR:33.0%(95%CI:22.4 - 43.6),BL:16.7%(95%CI:9.6 - 23.8),TL:4.0%(95%CI:0.0 - 8.5)。以下因素显著增加了PN的风险:成熟的牙根发育(风险比[HR]:7.50[95%CI:1.84 - 30.64],P = 0.005)和合并损伤(HR:2.68[95%CI:1.76 - 4.09],P < 0.001)。在逻辑回归模型中,成熟牙根的牙齿对牙髓测试无反应的风险增加了三倍。
采用保守治疗方法处理的孤立性牙槽突骨折累及牙齿似乎预后良好。最常见的并发症是PN,根管治疗后对牙齿的存活没有负面影响。