Morita Yoshihisa, Ayabe Kengo, Nurok Michael, Young Jerry
Department of Anesthesia, Indiana University School of Medicine, Fesler Hall Room 204, 1130 West Michigan St, Indianapolis, IN, 46202-5115.
Cardiac Surgery Intensive Care Unit, Department of Cardiothoracic Surgery, Cedars-Sinai Medical Center Heart Institute, 127 San Vicente Blvd Suite 3100, Los Angeles, CA, 90048.
J Clin Anesth. 2017 Feb;36:39-46. doi: 10.1016/j.jclinane.2016.09.030. Epub 2016 Nov 17.
Renal cell carcinoma has a tendency for vascular invasion and may extend into the inferior vena cava and even into the right-sided cardiac chambers. It has been reported that nephrectomy with thrombectomy can provide immediate palliation of symptoms with 5-year survival rates of up to 72% in the absence of nodal or distant metastasis. The location of the tumor dictates the anesthetic and surgical approach, as extension into the heart often necessitates cardiac surgical involvement. Renal cell carcinoma with vena cava tumor thrombus extending into the right cardiac chamber usually requires cardiopulmonary bypass and occasionally deep hypothermic circulatory arrest for surgical resection, and anesthetic approach should be tailored to each individual case. Thorough preoperative evaluation and the commitment of a multidisciplinary surgery team are indispensable.
肾细胞癌有血管侵犯倾向,可能延伸至下腔静脉,甚至进入右侧心腔。据报道,肾切除术联合血栓切除术可立即缓解症状,在无淋巴结或远处转移的情况下,5年生存率高达72%。肿瘤的位置决定了麻醉和手术方式,因为肿瘤延伸至心脏通常需要心脏外科参与。伴有腔静脉瘤栓并延伸至右心腔的肾细胞癌通常需要体外循环,偶尔还需要深低温停循环进行手术切除,麻醉方法应根据具体病例进行调整。全面的术前评估和多学科手术团队的协作是必不可少的。