源自被忽视的脑脊膜膨出的鳞状细胞癌。
Squamous cell carcinoma arising from neglected meningocele.
作者信息
Wani Abrar A, Raswan Uday K, Malik Nayil K, Ramzan Altaf U, Lone Iqbal
机构信息
Department of Neurosurgery, Sher-i- Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
Department of Pathology, Sher-i- Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
出版信息
Surg Neurol Int. 2016 Dec 28;7(Suppl 44):S1147-S1149. doi: 10.4103/2152-7806.196928. eCollection 2016.
BACKGROUND
A neural tube defect (NTD) is a common congenital anomaly with an incidence of 6.57-8.21 per 1000 live births. Patients usually present early because of obvious swelling or due to neurological deficit. However, neglecting the obvious cystic swelling on the back till its transformation into malignant tumor is rare.
CASE DESCRIPTION
We describe a case of malignant transformation of meningocele in a 60-year-old man. Magnetic resonance imaging showed sacral meningocele. Neurological examination revealed intact motor and sensory examination with normal bladder and bowel function. There were no signs of meningitis and hydrocephalus. Excision was done and biopsy revealed it as squamous cell carcinoma.
CONCLUSION
Meningocele should be treated early and possibility of malignant change should be kept in mind in neglected cases presenting in adulthood.
背景
神经管缺陷（NTD）是一种常见的先天性异常，每1000例活产儿中的发病率为6.57 - 8.21。患者通常因明显肿胀或神经功能缺损而早期就诊。然而，忽视背部明显的囊性肿胀直至其转变为恶性肿瘤的情况较为罕见。
病例描述
我们描述了一名60岁男性脊膜膨出恶变的病例。磁共振成像显示为骶部脊膜膨出。神经学检查显示运动和感觉检查正常，膀胱和肠道功能正常。没有脑膜炎和脑积水的迹象。进行了切除手术，活检显示为鳞状细胞癌。
结论
脊膜膨出应尽早治疗，对于成年期出现的被忽视病例应考虑恶变的可能性。
Zotero 插件