Block Norman L, Kava Bruce R
Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Department of Urology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Indian J Urol. 2017 Jan-Mar;33(1):6-12. doi: 10.4103/0970-1591.195724.
Sarcoidosis is a multisystem disease that commonly involves the lungs, but may also present with extrapulmonary manifestations. Genitourinary (GU) tract involvement has been traditionally thought to be rare, but that view may underestimate the true prevalence of the disease due to the often, silent presentation thereof.
The literature pertaining to sarcoidosis from the general systemic point of view, etiology and therapy and with regard to specific organs was reviewed by identifying key words in a PubMed search. That material with special relevance to the Indian experience was emphasized.
There are a number of isolated case reports in the literature describing symptomatic and asymptomatic GU tract sarcoidosis. The world literature associated with the generalized syndrome was reviewed and summarized. Specific aspects of GU involvement are presented for each organ of the GU tract.
It is critical for the practicing clinician to have a working knowledge of the clinical manifestations of this disease as it involves the GU tract, as well as to be able to distinguish it from tuberculosis and the various malignancies that affect this organ system.
结节病是一种多系统疾病，通常累及肺部，但也可能出现肺外表现。传统上认为泌尿生殖系统（GU）受累较为罕见，但由于该病通常表现隐匿，这种观点可能低估了其实际患病率。
通过在PubMed搜索中识别关键词，对从全身角度、病因和治疗以及特定器官方面有关结节病的文献进行了综述。强调了与印度经验特别相关的资料。
文献中有许多孤立的病例报告描述了有症状和无症状的泌尿生殖系统结节病。对与全身性综合征相关的世界文献进行了综述和总结。针对泌尿生殖系统的每个器官，介绍了泌尿生殖系统受累的具体方面。
对于执业临床医生来说，了解这种疾病累及泌尿生殖系统时的临床表现，并能够将其与结核病以及影响该器官系统的各种恶性肿瘤区分开来至关重要。
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