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三株对粘细菌代谢产物卡罗内酯敏感性不同的19A血清型多重耐药临床分离株的全基因组序列

Complete Genome Sequences of Three Multidrug-Resistant Clinical Isolates of Serotype 19A with Different Susceptibilities to the Myxobacterial Metabolite Carolacton.

作者信息

Donner Jannik, Bunk Boyke, Schober Isabel, Spröer Cathrin, Bergmann Simone, Jarek Michael, Overmann Jörg, Wagner-Döbler Irene

机构信息

Department of Medical Microbiology, Research Group Microbial Communication, Helmholtz Centre for Infection Research, Braunschweig, Germany

Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany and German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Braunschweig, Germany.

出版信息

Genome Announc. 2017 Feb 16;5(7):e01641-16. doi: 10.1128/genomeA.01641-16.

Abstract

The full-genome sequences of three drug- and multidrug-resistant clinical isolates of serotype 19A were determined by PacBio single-molecule real-time sequencing, in combination with Illumina MiSeq sequencing. A comparison to the genomes of other pneumococci indicates a high nucleotide sequence identity to strains Hungary19A-6 and TCH8431/19A.

摘要

通过PacBio单分子实时测序结合Illumina MiSeq测序,确定了3株19A血清型耐多药临床分离株的全基因组序列。与其他肺炎球菌基因组的比较表明,其与匈牙利19A - 6菌株和TCH8431/19A菌株具有高度的核苷酸序列同一性。

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