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内镜超声引导下胆囊引流治疗急性胆囊炎:自膨式金属支架取出后的长期疗效

Endoscopic ultrasound-guided gallbladder drainage for acute cholecystitis: Long-term outcomes after removal of a self-expandable metal stent.

作者信息

Kamata Ken, Takenaka Mamoru, Kitano Masayuki, Omoto Shunsuke, Miyata Takeshi, Minaga Kosuke, Yamao Kentaro, Imai Hajime, Sakurai Toshiharu, Watanabe Tomohiro, Nishida Naoshi, Kudo Masatoshi

机构信息

Ken Kamata, Mamoru Takenaka, Masayuki Kitano, Shunsuke Omoto, Takeshi Miyata, Kosuke Minaga, Kentaro Yamao, Hajime Imai, Toshiharu Sakurai, Tomohiro Watanabe, Naoshi Nishida, Masatoshi Kudo, Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama 589-8511, Japan.

出版信息

World J Gastroenterol. 2017 Jan 28;23(4):661-667. doi: 10.3748/wjg.v23.i4.661.

Abstract

AIM

To assess the long-term outcomes of this procedure after removal of self-expandable metal stent (SEMS). The efficacy and safety of endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) with SEMS were also assessed.

METHODS

Between January 2010 and April 2015, 12 patients with acute calculous cholecystitis, who were deemed unsuitable for cholecystectomy, underwent EUS-GBD with a SEMS. EUS-GBD was performed under the guidance of EUS and fluoroscopy, by puncturing the gallbladder with a needle, inserting a guidewire, dilating the puncture hole, and placing a SEMS. The SEMS was removed and/or replaced with a 7-Fr plastic pigtail stent after cholecystitis improved. The technical and clinical success rates, adverse event rate, and recurrence rate were all measured.

RESULTS

The rates of technical success, clinical success, and adverse events were 100%, 100%, and 0%, respectively. After cholecystitis improved, the SEMS was removed without replacement in eight patients, whereas it was replaced with a 7-Fr pigtail stent in four patients. Recurrence was seen in one patient (8.3%) who did not receive a replacement pigtail stent. The median follow-up period after EUS-GBD was 304 d (78-1492).

CONCLUSION

EUS-GBD with a SEMS is a possible alternative treatment for acute cholecystitis. Long-term outcomes after removal of the SEMS were excellent. Removal of the SEMS at 4-wk after SEMS placement and improvement of symptoms might avoid migration of the stent and recurrence of cholecystitis due to food impaction.

摘要

目的

评估自膨式金属支架(SEMS)取出术后该手术的长期疗效。同时评估内镜超声引导下经SEMS行胆囊引流术(EUS-GBD)的有效性和安全性。

方法

2010年1月至2015年4月,12例被认为不宜行胆囊切除术的急性结石性胆囊炎患者接受了经SEMS的EUS-GBD治疗。EUS-GBD在EUS和荧光透视引导下进行,通过用针穿刺胆囊、插入导丝、扩张穿刺孔并放置SEMS。胆囊炎改善后取出SEMS并用7F塑料猪尾支架进行置换。测量技术成功率、临床成功率、不良事件发生率和复发率。

结果

技术成功率、临床成功率和不良事件发生率分别为100%、100%和0%。胆囊炎改善后,8例患者取出SEMS未进行置换,而4例患者用7F猪尾支架进行了置换。1例未接受猪尾支架置换的患者出现复发(8.3%)。EUS-GBD后的中位随访期为304天(78-1492天)。

结论

经SEMS的EUS-GBD是急性胆囊炎的一种可能的替代治疗方法。取出SEMS后的长期疗效良好。在放置SEMS后4周取出SEMS并改善症状可能避免支架移位和因食物嵌塞导致的胆囊炎复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84c3/5292340/6904e4a1659e/WJG-23-661-g001.jpg

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