Enzymatic transformation of leukotriene A4 into 5,6-dihydroxy-7,9,11, 14-eicosatetraenoic acid.
作者信息
Haeggström J, Meijer J, Rådmark O
机构信息
Department of Physiological Chemistry, Karolinska Institutet, Stockholm, Sweden.
出版信息
Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:134-9.
PMID:2821753
Abstract
摘要
相似文献
1
Enzymatic transformation of leukotriene A4 into 5,6-dihydroxy-7,9,11, 14-eicosatetraenoic acid.
Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:134-9.
2
14,15-Dihydroxy-5,8,10,12-eicosatetraenoic acid. Enzymatic formation from 14,15-leukotriene A4.
Eur J Biochem. 1988 May 2;173(3):531-6. doi: 10.1111/j.1432-1033.1988.tb14031.x.
3
Evidence for a carbocation intermediate in the enzymatic transformation of leukotriene A4 into leukotriene B4.
Adv Exp Med Biol. 1999;469:319-25. doi: 10.1007/978-1-4615-4793-8_47.
4
5
Enzymatic formation of 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid: kinetics of the reaction and stereochemistry of the product.
Biochim Biophys Acta. 1988 Feb 19;958(3):469-76. doi: 10.1016/0005-2760(88)90233-0.
6
Mutation of tyrosine 383 in leukotriene A4 hydrolase allows conversion of leukotriene A4 into 5S,6S-dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acid. Implications for the epoxide hydrolase mechanism.白三烯A4水解酶中酪氨酸383的突变使得白三烯A4转化为5S,6S-二羟基-7,9-反式-11,14-顺式-二十碳四烯酸。对环氧化物水解酶机制的影响。
J Biol Chem. 1997 Sep 12;272(37):23057-63. doi: 10.1074/jbc.272.37.23057.
7
Enzymatic hydrolysis of leukotriene A4 into 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid and LTB4 by mammalian kidney.哺乳动物肾脏将白三烯A4酶水解为5,6-二羟基-7,9,11,14-二十碳四烯酸和白三烯B4 。
Biochem Biophys Res Commun. 1987 Mar 13;143(2):697-703. doi: 10.1016/0006-291x(87)91410-0.
8
Cytosolic liver enzymes catalyzing hydrolysis of leukotriene A4 to leukotriene B4 and 5,6-dihydroxyeicosatetraenoic acid.
Methods Enzymol. 1990;187:324-34. doi: 10.1016/0076-6879(90)87038-5.
9
10
Biosynthesis and further transformations of leukotriene A4.白三烯A4的生物合成及进一步转化
Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:64-8.
Zotero 插件