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小、中、大型先天性黑素细胞痣的皮肤镜特征

Dermoscopic Features of Small, Medium, and Large-Sized Congenital Melanocytic Nevi.

作者信息

Cengiz Fatma Pelin, Emiroglu Nazan, Ozkaya Dilek Biyik, Su Ozlem, Onsun Nahide

机构信息

Department of Dermatology, Bezmialem Vakif University, Istanbul, Turkey.

出版信息

Ann Dermatol. 2017 Feb;29(1):26-32. doi: 10.5021/ad.2017.29.1.26. Epub 2017 Feb 3.

Abstract

BACKGROUND

Congenital melanocytic nevi (CMN) are present at birth. It is well known that the presence of large-sized congenital nevus in early life could predict a major risk of developing melanoma.

OBJECTIVE

To investigate the clinical and dermoscopic features of the CMN, to search for and highlight any differences between small-sized, medium-sized, large-sized CMN.

METHODS

A nonrandomized observational study was performed. A total of 108 melanocytic nevi were analysed by clinical and dermoscopic examination.

RESULTS

Of the subjects, 57.4% were aged less than 16 years, 42.6% were aged 16 and more. Of the nevi, 26 had reticular pattern (24.1%), 35 had globular pattern (32.4%), 13 had reticular-globular pattern (12.0%), 16 had homogeneous pattern (14.8%), 6 had reticular-homogeneous pattern (5.6%), 2 had globular-homogeneous pattern (1.9%), 7 had cobblestone pattern (6.5%), 3 had reticular patchy pattern (2.8%). Atypical dots and globules, focal hypopigmentation and perifollicular hypopigmentation are the most common dermoscopic features of CMN. The rarest dermoscopic feature is the blue-whitish veil.

CONCLUSION

Most of the dermoscopic features related with dysplastic nevi up to the present, such as atypical dots and globules, focal hypopigmentation, perifollicular hypopigmentation were observed in CMN, in our study. Congenital nevus and dysplastic nevi may share the same dermoscopic features, therefore it is important to know it is found at birth or not.

摘要

背景

先天性黑素细胞痣(CMN)在出生时即存在。众所周知,早年出现的大型先天性痣可能预示着发生黑色素瘤的重大风险。

目的

研究CMN的临床和皮肤镜特征,寻找并突出小、中、大型CMN之间的差异。

方法

进行了一项非随机观察性研究。通过临床和皮肤镜检查对总共108个黑素细胞痣进行了分析。

结果

在这些受试者中,57.4%年龄小于16岁,42.6%年龄在16岁及以上。在这些痣中,26个具有网状模式(24.1%),35个具有球状模式(32.4%),13个具有网状 - 球状模式(12.0%),16个具有均匀模式(14.8%),6个具有网状 - 均匀模式(5.6%),2个具有球状 - 均匀模式(1.9%),7个具有鹅卵石样模式(6.5%),3个具有网状斑片状模式(2.8%)。非典型点和球状体、局灶性色素减退和毛囊周围色素减退是CMN最常见的皮肤镜特征。最罕见的皮肤镜特征是蓝白色薄纱。

结论

在我们的研究中,CMN中观察到了目前与发育异常痣相关的大多数皮肤镜特征,如非典型点和球状体、局灶性色素减退、毛囊周围色素减退。先天性痣和发育异常痣可能具有相同的皮肤镜特征,因此了解它是否在出生时就被发现很重要。

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