Maue Danielle K, Krupp Nadia, Rowan Courtney M
Danielle K Maue, Courtney M Rowan, Department of Pediatric Critical Care, Indiana University School of Medicine, Indianapolis, IN 46202, United States.
World J Clin Pediatr. 2017 Feb 8;6(1):34-39. doi: 10.5409/wjcp.v6.i1.34.
To determine if a standardized asthma severity scoring system (PASS) was associated with the time spent on continuous albuterol and length of stay in the pediatric intensive care unit (PICU).
This is a single center, retrospective chart review study at a major children's hospital in an urban location. To qualify for this study, participants must have been admitted to the PICU with a diagnosis of status asthmaticus. There were a total of 188 participants between the ages of two and nineteen, excluding patients receiving antibiotics for pneumonia. PASS was calculated upon PICU admission. Subjects were put into one of three categories based on PASS: ≤ 7 (mild), 8-11 (moderate), and ≥ 12 (severe). The groups were compared based on different variables, including length of continuous albuterol and PICU stay.
The age distribution across all groups was similar. The median length of continuous albuterol was longest in the severe group with a duration of 21.5 h (11.5-27.5), compared to 15 (7.75-23.75) and 10 (5-15) in the moderate and mild groups, respectively ( = 0.001). The length of stay was longest in the severe group, with a stay of 35.6 h (22-49) compared to 26.5 (17-30) and 17.6 (12-29) in the moderate and mild groups, respectively ( = 0.001).
A higher PASS is associated with a longer time on continuous albuterol, an increased likelihood to require noninvasive ventilation, and a longer stay in the ICU. This may help safely distribute asthmatics to lower and higher levels of care in the future.
确定标准化哮喘严重程度评分系统（PASS）是否与持续使用沙丁胺醇的时间及在儿科重症监护病房（PICU）的住院时间相关。
这是一项在城市一家大型儿童医院进行的单中心回顾性病历审查研究。符合本研究条件的参与者必须因哮喘持续状态诊断而入住PICU。共有188名年龄在2岁至19岁之间的参与者，排除因肺炎接受抗生素治疗的患者。PASS在入住PICU时计算。根据PASS将受试者分为三类之一：≤7（轻度）、8 - 11（中度）和≥12（重度）。根据不同变量对各组进行比较，包括持续使用沙丁胺醇的时间和PICU住院时间。
所有组的年龄分布相似。重度组持续使用沙丁胺醇的中位时间最长，为21.5小时（11.5 - 27.5），而中度组和轻度组分别为15小时（7.75 - 23.75）和10小时（5 - 15）（P = 0.001）。重度组的住院时间最长，为35.6小时（22 - 49），而中度组和轻度组分别为26.5小时（17 - 30）和17.6小时（12 - 29）（P = 0.001）。
较高的PASS与持续使用沙丁胺醇的时间更长、需要无创通气的可能性增加以及在ICU的住院时间更长相关。这可能有助于未来将哮喘患者安全地分配到不同级别的护理中。
