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使用原位自体组织重建肺后壁治疗室间隔缺损合并肺动脉闭锁

Reconstruction of the pulmonary posterior wall using in situ autologous tissue for the treatment of pulmonary atresia with ventricular septal defect.

作者信息

Fan Chengming, Yang Yifeng, Xiong Lian, Yin Ni, Wu Qin, Tang Mi, Yang Jinfu

机构信息

Department of the cardiovascular surgery, the Second Xiangya Hospital, Central South University, Middle Renmin Road 139, 410011, Changsha, China.

出版信息

J Cardiothorac Surg. 2017 Feb 23;12(1):12. doi: 10.1186/s13019-017-0578-4.

Abstract

BACKGROUND

To evaluate the early and mid-term results of pulmonary trunk reconstruction using a technique in which autogenous tissue is preserved in situ in pulmonary atresia patients with a ventricular septal defect (PA-VSD).

METHODS

The pulmonary artery was reconstructed using autogenous tissue that had been preserved in situ and a bovine jugular venous patch in 24 patients who were diagnosed with PA-VSD (the observation group). The traditional operation using a bovine jugular venous conduit was performed in 40 other cases of PA-VSD (the control group).

RESULTS

In the observation group, all patients survived and recovered successfully without complications. Follow-up echocardiography 2-10 years after the procedure showed that the reconstructed right ventricular outflow tract (RVOT) and pulmonary artery were patent, showing no evidence of flow obstruction. Only mild regurgitation of the bovine jugular vein valve was observed. In the control group, early postoperative death occurred in two cases. Another two patients had obstruction of the anastomotic stoma and underwent conduit replacement surgery within 2 weeks of the initial procedure. During the 2-10 years of follow-up care, six patients presented with valvular stenosis of the BJVC, with a pressure gradient of more than 50 mmHg.

CONCLUSIONS

The technique for preserving autogenous tissue to reconstruct the pulmonary posterior wall is a satisfactory method for treating PA-VSD.

摘要

背景

评估采用自体组织原位保留技术对室间隔缺损合并肺动脉闭锁(PA-VSD)患者进行肺动脉干重建的早期和中期结果。

方法

对24例诊断为PA-VSD的患者(观察组),采用原位保留的自体组织和牛颈静脉补片重建肺动脉。另外40例PA-VSD患者(对照组)采用传统的牛颈静脉导管手术。

结果

观察组所有患者均存活且顺利康复,无并发症。术后2至10年的超声心动图随访显示,重建的右心室流出道(RVOT)和肺动脉通畅,无血流梗阻迹象。仅观察到牛颈静脉瓣膜轻度反流。对照组术后早期有2例死亡。另外2例患者吻合口狭窄,在初次手术后2周内接受了导管置换手术。在2至10年的随访期间,6例患者出现牛颈静脉导管瓣膜狭窄,压力阶差超过50 mmHg。

结论

保留自体组织重建肺动脉后壁的技术是治疗PA-VSD的一种令人满意的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8144/5324245/a16dba8847c8/13019_2017_578_Fig1_HTML.jpg

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