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使用微翅片结构稳定离子浓差极化层,实现高通量应用。

Stabilization of ion concentration polarization layer using micro fin structure for high-throughput applications.

机构信息

Department of Electrical and Computer Engineering, Seoul National University, Seoul 08826, South Korea.

出版信息

Nanoscale. 2017 Mar 9;9(10):3466-3475. doi: 10.1039/c6nr08978j.

Abstract

Ion concentration polarization (ICP) has been extensively researched concerning new fundamentals in nanoscale electrokinetics and novel engineering applications. While biomedical and environmental ICP applications have a number of advantages compared to conventional methods, the technique has suffered from the critical limitation of low processing capacity because it has been usually presented in a micro/nanofluidic platform. In this paper, we devised micro fin structures inside a macroscale high-throughput ICP device and successfully demonstrated a stable formation of ICP layer and its performance. Since the fin structures created surface conductive fluidic circumstances and assisted in physically suppressing undesirable electrokinetic vortices generated in this fluidic regime, ICP was stably generated even in this macroscale system. Finally, batch-type droplet ICP preconcentrator and continuous-type ICP separator were introduced as examples for high-throughput millimeter-scale ICP devices using the implanted fin structures.

摘要

离子浓差极化 (ICP) 在纳米尺度电动学的新基础和新型工程应用方面的研究已经非常广泛。虽然与传统方法相比,生物医学和环境 ICP 应用具有许多优势,但该技术一直受到处理能力低的严重限制,因为它通常在微/纳流控平台中呈现。在本文中,我们在宏观高通量 ICP 装置内设计了微鳍结构,并成功地展示了 ICP 层的稳定形成及其性能。由于鳍结构创造了表面导电流型环境,并有助于在物理上抑制在该流型中产生的不良电动涡旋,因此即使在这个宏观系统中也能稳定地产生 ICP。最后,作为使用植入鳍结构的高通量毫米尺度 ICP 装置的示例,介绍了批量式液滴 ICP 预浓缩器和连续式 ICP 分离器。

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