Noguchi Keita, Nishizawa Yuji, Komai Yoshinobu, Sakai Yasuyuki, Kobayasi Akihiro, Ito Masaaki, Saito Norio
Department of Colorectal and Pelvic Surgery, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa-City, Chiba, 277-8577, Japan.
Department of Urology, National Cancer Center Hospital East, Kashiwa, Japan.
Surg Today. 2017 Sep;47(9):1119-1128. doi: 10.1007/s00595-017-1484-z. Epub 2017 Mar 4.
Sphincter-preserving operations performed with bladder-preserving surgery and a cystourethral anastomosis (CUA) do not require a urinary stoma, but leakage from the CUA may develop. The aim of this study was to evaluate the efficacy of performing an additional flap operation.
The subjects were 39 patients who underwent bladder-preserving surgery for advanced rectal cancer involving the prostate, between 2001 and 2015.32 of whom had a CUA and one of whom had a neobladder. Five of these 32 patients underwent an ileal flap operation, 2 underwent an omental flap operation, and 3 underwent an operation using both flaps.
Leakage developed in 3 (30%) of the 10 patients who underwent additional flap operations, but in 14 (60.9%) of the 23 patients who did not undergo a flap operation. The mean periods of catheterization for the patients who suffered leakage were 31 weeks (8-108 weeks) in those without a flap and 16 weeks (8-20 weeks) in those with a flap. Four (33.3%) of the 12 patients with leakage after surgery without a flap had a period of urinary catheterization >30 weeks, and 2 (16.7%) had leakage of CTCAE grade 3. There were no cases of leakage after flap surgery.
An additional flap operation may decrease the risk of leakage from a CUA.
保留括约肌的手术结合保留膀胱手术及膀胱尿道吻合术(CUA)无需造口,但CUA可能发生漏尿。本研究旨在评估额外进行皮瓣手术的疗效。
研究对象为2001年至2015年间因晚期直肠癌累及前列腺而接受保留膀胱手术的39例患者。其中32例行CUA,1例行新膀胱术。这32例患者中,5例行回肠皮瓣手术,2例行网膜皮瓣手术,3例行两种皮瓣联合手术。
接受额外皮瓣手术的10例患者中有3例(30%)发生漏尿,而未进行皮瓣手术的23例患者中有14例(60.9%)发生漏尿。发生漏尿的患者中,未行皮瓣手术者的平均导尿时间为31周(8 - 108周),行皮瓣手术者为16周(8 - 20周)。未行皮瓣手术的12例术后漏尿患者中有4例(33.3%)导尿时间>30周,2例(16.7%)为3级CTCAE漏尿。皮瓣手术后无漏尿病例。
额外进行皮瓣手术可能降低CUA漏尿风险。