Saha M, Nahar K, Parveen I, Mahmuduzzaman M, Hosen M A, Mutsuddy P, Khan M H
Dr Madhusudan Saha, Associate Professor, Department of Gastroenterology, North East Medical College, Sylhet, Bangladesh; E-email:
Mymensingh Med J. 2017 Jan;26(1):109-116.
This hospital-based study was done to see the prevalence of sonologically detected non alcoholic fatty liver disease and associated factors in the apparently healthy adults. Apparently healthy and non alcoholic companions of the patients visiting the Centre of Nuclear Medicine and Ultrasound, Sylhet were subjected to abdominal ultrasonography to see the presence of fatty liver. Demographic features and other relevant data were collected in a semi structured questionnaire to find out the associated factors for non alcoholic fatty liver disease (NAFLD). Total 1019 persons with mean age of 37.23 years were included in the study. Among them 703 (69%) were female and 316 (31%) were male. Out of them 189 (18.5%) persons had sonologically detectable nonalcoholic fatty liver disease. NAFLD was more prevalent in male than female (25.6% vs. 15.4%, p=0.000). In univariate analysis NAFLD were more in male (25.6%) 41-50 years age group (29.3%, p=0.000), over weight (32.3%)/obese subjects (51.4%), businessmen (24.0%), service holders (28.7%), high income group, diabetics (27.0% vs. 18.0%, p=0.000) and hypertensive subjects (43.3% vs. 15.24%, p=0.000). In multivariate analysis, BMI over 23kg/m² (OR 6.683, p=0.000), age >30 years (OR 1.787, p=0.006) and higher income (OR 1.788, 95% CI 0.970-3.293) were independent factors associated with NAFLD. Sonologically detected nonalcoholic fatty liver disease (18.5%) is common in our apparently healthy adults. BMI over 23kg/m² was the most important predictor for NAFLD.
这项基于医院的研究旨在观察在表面健康的成年人中,超声检查发现的非酒精性脂肪性肝病的患病率及其相关因素。前往锡尔赫特核医学与超声中心就诊的患者的表面健康且非酒精性的同伴接受了腹部超声检查,以查看是否存在脂肪肝。通过半结构化问卷收集人口统计学特征和其他相关数据,以找出非酒精性脂肪性肝病(NAFLD)的相关因素。共有1019人纳入研究,平均年龄为37.23岁。其中703人(69%)为女性,316人(31%)为男性。其中189人(18.5%)经超声检查发现患有非酒精性脂肪性肝病。NAFLD在男性中比女性更普遍(25.6%对15.4%,p = 0.000)。单因素分析显示,NAFLD在男性(25.6%)、41 - 50岁年龄组(29.3%,p = 0.000)、超重(32.3%)/肥胖受试者(51.4%)、商人(24.0%)、服务业从业者(28.7%)、高收入群体、糖尿病患者(27.0%对18.0%,p = 0.000)和高血压患者(43.3%对15.24%,p = 0.000)中更为常见。多因素分析显示,体重指数超过23kg/m²(OR 6.683,p = 0.000)、年龄大于30岁(OR 1.787,p = 0.006)和高收入(OR 1.788,95%CI 0.970 - 3.293)是与NAFLD相关的独立因素。经超声检查发现的非酒精性脂肪性肝病(18.5%)在我们表面健康的成年人中很常见。体重指数超过23kg/m²是NAFLD最重要的预测因素。