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术后谵妄是老年(≥65岁)脊柱手术后30天内再次入院的独立预测因素:一项对453例连续老年脊柱手术患者的研究。

Post-operative delirium is an independent predictor of 30-day hospital readmission after spine surgery in the elderly (≥65years old): A study of 453 consecutive elderly spine surgery patients.

作者信息

Elsamadicy Aladine A, Wang Timothy Y, Back Adam G, Lydon Emily, Reddy Gireesh B, Karikari Isaac O, Gottfried Oren N

机构信息

Department of Neurosurgery, Duke University Medical Center, Durham, NC, United States.

Department of Neurosurgery, Duke University Medical Center, Durham, NC, United States.

出版信息

J Clin Neurosci. 2017 Jul;41:128-131. doi: 10.1016/j.jocn.2017.02.040. Epub 2017 Mar 2.

Abstract

In the last decade, costs of U.S. healthcare expenditures have been soaring, with billions of dollars spent on hospital readmissions. Identifying causes and risk factors can reduce soaring readmission rates and help lower healthcare costs. The aim of this is to determine if post-operative delirium in the elderly is an independent risk factor for 30-day hospital readmission after spine surgery. The medical records of 453 consecutive elderly (≥65years old) patients undergoing spine surgery at Duke University Medical Center from 2008 to 2010 were reviewed. We identified 17 (3.75%) patients who experienced post-operative delirium according to DSM-V criteria. Patient demographics, comorbidities, and post-operative complication rates were collected for each patient. Elderly patients experiencing post-operative delirium had an increased length of hospital stay (10.47days vs. 5.70days, p=0.009). Complication rates were similar between the cohorts with the post-operative delirium patients having increased UTI and superficial surgical site infections. In total, 12.14% of patients were re-admitted within 30-days of discharge, with post-operative delirium patients experiencing approximately a 4-fold increase in 30-day readmission rates (Delirium: 41.18% vs. No Delirium: 11.01%, p=0.002). In a multivariate logistic regression analysis, post-operative delirium is an independent predictor of 30-day readmission after spine surgery in the elderly (p=0.03). Elderly patients experiencing post-operative delirium after spine surgery is an independent risk factor for unplanned readmission within 30-days of discharge. Preventable measures and early awareness of post-operative delirium in the elderly may help reduce readmission rates.

摘要

在过去十年中,美国医疗保健支出成本一直在飙升,其中数十亿美元花费在医院再入院方面。确定原因和风险因素可以降低居高不下的再入院率,并有助于降低医疗保健成本。本研究的目的是确定老年患者术后谵妄是否是脊柱手术后30天内医院再入院的独立危险因素。回顾了2008年至2010年在杜克大学医学中心连续接受脊柱手术的453例老年(≥65岁)患者的病历。根据《精神疾病诊断与统计手册》第五版(DSM-V)标准,我们确定了17例(3.75%)经历术后谵妄的患者。收集了每位患者的人口统计学数据、合并症和术后并发症发生率。经历术后谵妄的老年患者住院时间延长(10.47天对5.70天,p=0.009)。两组的并发症发生率相似,术后谵妄患者的尿路感染和浅表手术部位感染有所增加。总共有12.14%的患者在出院后30天内再次入院,术后谵妄患者的30天再入院率增加了约4倍(谵妄:41.18%对无谵妄:11.01%,p=0.002)。在多因素逻辑回归分析中,术后谵妄是老年患者脊柱手术后30天再入院的独立预测因素(p=0.03)。脊柱手术后经历术后谵妄的老年患者是出院后30天内非计划再入院的独立危险因素。针对老年患者术后谵妄的可预防措施和早期认识可能有助于降低再入院率。

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