Institute of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.
University Hospital Psychiatry Unit, Integrated Department of Mental Health and Addictive Behaviors, Health Authorities and University S. Anna Hospital, Ferrara, Italy.
Psychooncology. 2017 Nov;26(11):1965-1971. doi: 10.1002/pon.4413. Epub 2017 Mar 27.
Demoralization is a commonly observed syndrome in cancer patients, deserving to be carefully assessed in cross-cultural contexts.
To examine the factor structure and concurrent and divergent validity of the Italian version of the Demoralization Scale (DS-IT) in cancer patients.
The sample included 194 Italian cancer outpatients who were assessed by using the DS-IT and the Diagnostic Criteria of Psychosomatic Research-Demoralization module to examine demoralization. The Patient Health Questionnaire-9 (PHQ-9) to explore depression and the Mini-Mental Adjustment-to-Cancer-Hopelessness/Helplessness scale (Mini-MAC-HH) to explore maladaptive coping were also administered.
Four factors were extracted by exploratory factor analysis on the DS-IT (disheartenment, α = .87; sense of failure, α = .77; dysphoria, α = .73; loss of meaning/purpose, α = .72; total = 0.91), accounting for 57.1% of the variance. The DS-IT factors shared between 17% and 36% of the variance. Patients reporting a diagnosis of demoralization on the Diagnostic Criteria of Psychosomatic Research-Demoralization module (23.7%) had higher scores on DS-IT loss of meaning/purpose, sense of failure, dysphoria, and DS-IT total. About half of those who were highly demoralized were not depressed and among those who had moderate or moderately severe demoralization, about 80% were not depressed on the PHQ-9. The DS-IT was significantly associated with PHQ-9 and Mini-MAC-HH.
The study presents further evidence that demoralization is a significant clinical condition and that the DS-IT demonstrates satisfactory levels of validity and reliability to support its use in patients in the ambulatory cancer setting.
沮丧是癌症患者中常见的综合征,值得在跨文化环境中进行仔细评估。
检验意大利语版沮丧量表(DS-IT)在癌症患者中的因子结构以及同时性和发散性效度。
该样本包括 194 名意大利癌症门诊患者,他们接受了 DS-IT 和心理躯体研究沮丧诊断标准模块的评估,以检查沮丧。还使用患者健康问卷-9(PHQ-9)来探索抑郁,使用 Mini-Mental Adjustment-to-Cancer-Hopelessness/Helplessness Scale(Mini-MAC-HH)来探索适应性应对。
通过对 DS-IT 的探索性因素分析提取了四个因素(灰心,α=0.87;失败感,α=0.77;烦躁,α=0.73;失去意义/目的,α=0.72;总分=0.91),占方差的 57.1%。DS-IT 因素之间的共享方差为 17%至 36%。在心理躯体研究沮丧诊断标准模块上报告沮丧诊断的患者(23.7%)在 DS-IT 失去意义/目的、失败感、烦躁和 DS-IT 总分上的得分更高。大约一半高度沮丧的患者没有抑郁,在中度或中度严重沮丧的患者中,约 80%的 PHQ-9 没有抑郁。DS-IT 与 PHQ-9 和 Mini-MAC-HH 显著相关。
该研究进一步证明沮丧是一种重要的临床状况,DS-IT 具有令人满意的效度和信度水平,可支持其在门诊癌症患者中的使用。