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跖骨头切除术与保守治疗在糖尿病神经病变足溃疡治疗中的比较

Comparison of Metatarsal Head Resection Versus Conservative Care in Treatment of Neuropathic Diabetic Foot Ulcers.

作者信息

Kalantar Motamedi Alireza, Ansari Mohammad

机构信息

Assistant Professor of General Surgery, Subspecialist in Vascular Surgery, Department of Surgery, Rasoul-e-Akram Hospital, Iran University of Medical Science, Tehran, Iran.

General Practitioner, Department of Surgery, Rasoul-e-Akram Hospital, Iran University of Medical Science, Tehran, Iran.

出版信息

J Foot Ankle Surg. 2017 May-Jun;56(3):428-433. doi: 10.1053/j.jfas.2016.11.019. Epub 2017 Mar 3.

Abstract

Complications from diabetic foot ulcers often lead to increased patient morbidity. Much debate still ensues concerning surgical versus conservative management of neuropathic diabetic foot ulcerations. The present study assessed and compared the efficacy of metatarsal head resection and medical approach in the treatment of neuropathic diabetic foot ulcers located at the plantar surface of metatarsal heads. In a retrospective cohort study, 24 consecutive neuropathic diabetic foot ulcers in the lower area of the metatarsal heads that had undergone metatarsal head resection were included as the operative group. For the control group, we included 25 similar ulcers that were scheduled for medical therapy. With respect to postoperative complications, wound healing occurred earlier in the operative group, and the recurrence rate was inversely greater in the medical treatment group. Also, the hospitalization rate was significantly greater in the medical treatment group. Overall, the long-term complication rate was lower in the operative than in the medical treatment group. Also, the infection rate was greater in the medical treatment group than in the operative group. Comparing early and late clinical outcomes of metatarsal head resection surgery and medical treatment showed complete superiority for the surgical approach, and metatarsal head resection is more completely cost beneficial than the medical approach.

摘要

糖尿病足溃疡的并发症常常导致患者发病率增加。关于神经性糖尿病足溃疡的手术治疗与保守治疗仍存在诸多争议。本研究评估并比较了跖骨头切除术与药物治疗方法在治疗位于跖骨头足底表面的神经性糖尿病足溃疡中的疗效。在一项回顾性队列研究中,将连续24例接受跖骨头切除术的位于跖骨头下部区域的神经性糖尿病足溃疡纳入手术组。对于对照组,我们纳入了25例计划接受药物治疗的类似溃疡。关于术后并发症,手术组伤口愈合更早,而药物治疗组的复发率反而更高。此外,药物治疗组的住院率显著更高。总体而言,手术组的长期并发症发生率低于药物治疗组。而且,药物治疗组的感染率高于手术组。比较跖骨头切除术与药物治疗的早期和晚期临床结果显示,手术方法具有完全的优越性,并且跖骨头切除术比药物治疗方法在成本效益上更具优势。

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