Funk L M, Gunnar W, Dominitz J A, Eisenberg D, Frayne S, Maggard-Gibbons M, Kalarchian M A, Livingston E, Sanchez V, Smith B R, Weidenbacher H, Maciejewski Matthew L
William S. Middleton VA Hospital, Madison, WI, USA.
Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA.
J Gen Intern Med. 2017 Apr;32(Suppl 1):65-69. doi: 10.1007/s11606-016-3951-4.
In 2016, the Veterans Health Administration (VHA) held a Weight Management State of the Art conference to identify evidence gaps and develop a research agenda for population-based weight management for veterans. Included were behavioral, pharmacologic, and bariatric surgery workgroups. This article summarizes the bariatric surgery workgroup (BSWG) findings and recommendations for future research. The BSWG agreed that there is evidence from randomized trials and large observational studies suggesting that bariatric surgery is superior to medical therapy for short- and intermediate-term remission of type 2 diabetes, long-term weight loss, and long-term survival. Priority evidence gaps include long-term comorbidity remission, mental health, substance abuse, and health care costs. Evidence of the role of endoscopic weight loss options is also lacking. The BSWG also noted the limited evidence regarding optimal timing for bariatric surgery referral, barriers to bariatric surgery itself, and management of high-risk bariatric surgery patients. Clinical trials of pre- and post-surgery interventions may help to optimize patient outcomes. A registry of overweight and obese veterans and a workforce assessment to determine the VHA's capacity to increase bariatric surgery access were recommended. These will help inform policy modifications and focus the research agenda to improve the ability of the VHA to deliver population-based weight management.
2016年,退伍军人健康管理局(VHA)召开了一次体重管理技术现状会议,以确定证据空白,并为退伍军人的群体体重管理制定研究议程。会议涵盖了行为、药物和减肥手术工作组。本文总结了减肥手术工作组(BSWG)的研究结果以及对未来研究的建议。BSWG一致认为,随机试验和大型观察性研究的证据表明,减肥手术在2型糖尿病的短期和中期缓解、长期体重减轻以及长期生存方面优于药物治疗。优先证据空白包括长期合并症缓解、心理健康、药物滥用和医疗保健成本。内镜减肥方法的作用证据也很缺乏。BSWG还指出,关于减肥手术转诊的最佳时机、减肥手术本身的障碍以及高危减肥手术患者的管理,证据有限。手术前后干预的临床试验可能有助于优化患者预后。建议建立一个超重和肥胖退伍军人登记处,并进行劳动力评估,以确定VHA增加减肥手术可及性的能力。这些将有助于为政策调整提供信息,并聚焦研究议程,以提高VHA提供群体体重管理的能力。