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2至12个月龄流感/呼吸道合胞病毒检测呈阳性的发热婴儿的尿路感染检测

Testing for Urinary Tract Infection in the Influenza/Respiratory Syncytial Virus-Positive Febrile Infant Aged 2 to 12 Months.

作者信息

Schlechter Salinas Anna Kathleen, Hains David S, Jones Tamekia, Harrell Camden, Meredith Mark

机构信息

From the Pediatric Emergency Medicine Fellowship, Dell Children's Medical Center of Central Texas, University of Texas at Austin Dell Medical School, Austin, TX.

Innate Immunity Translational Research Center.

出版信息

Pediatr Emerg Care. 2019 Oct;35(10):666-670. doi: 10.1097/PEC.0000000000001073.

Abstract

OBJECTIVE

Infants 12 months or younger with influenza and respiratory syncytial virus (RSV) commonly present to the emergency department (ED) with fever. Previous publications have recommended that these patients have a urinalysis and urine culture performed. We aimed to assess the prevalence of urinary tract infection (UTI) in febrile RSV/influenza positive infants aged 2 to 12 months presenting to the ED. We also examined whether the 2011 American Academy of Pediatrics (AAP) UTI clinical practice guidelines could be used to identify patients at lower risk of UTI.

METHODS

This was a retrospective chart review examining all infants aged 2 to 12 months with a documented fever of higher than 38°C who presented to our ED from 2009 to 2013 and tested positive for influenza and/or RSV.

RESULTS

One thousand seven hundred twenty-four patients were found to meet our inclusion criteria. Of these, 98 were excluded because of known urinary tract anomaly or systemic antibiotic use in the 24 hours preceding evaluation. Of those patients remaining, 10 (0.62%) of 1626 had positive urine cultures (95% confidence interval, 0.3%-1.1%), and 8 (0.49%) of 1626 (95% confidence interval, 0.2%-0.97%) had positive urine cultures with positive urinalyses as defined in the 2011 AAP UTI clinical practice guidelines. All subjects with positive urine cultures as defined by the AAP had risk factors for UTI that placed their risk for UTI above 1%.

CONCLUSIONS

Our population of 2- to 12-month-old febrile infants with positive influenza/RSV testing, who did not have risk factors to make their risk of UTI higher than 1%, may not have required evaluation with urinalysis or urine culture.

摘要

目的

12个月及以下感染流感和呼吸道合胞病毒(RSV)的婴儿常因发热前往急诊科(ED)就诊。既往出版物建议对这些患者进行尿常规和尿培养检查。我们旨在评估2至12个月大、因发热前来ED就诊且RSV/流感检测呈阳性的婴儿中尿路感染(UTI)的患病率。我们还研究了2011年美国儿科学会(AAP)的UTI临床实践指南是否可用于识别UTI风险较低的患者。

方法

这是一项回顾性病历审查,研究对象为2009年至2013年期间因发热高于38°C前来我院ED就诊且流感和/或RSV检测呈阳性的所有2至12个月大的婴儿。

结果

共发现1724例患者符合纳入标准。其中,98例因已知尿路异常或在评估前24小时内使用全身性抗生素而被排除。在剩余患者中,1626例中有10例(0.62%)尿培养呈阳性(95%置信区间,0.3%-1.1%),1626例中有8例(0.49%)尿培养呈阳性且尿常规符合2011年AAP UTI临床实践指南中定义的阳性标准(95%置信区间,0.2%-0.97%)。所有AAP定义的尿培养阳性的受试者均有UTI危险因素,其UTI风险高于1%。

结论

对于我们研究的2至12个月大、流感/RSV检测呈阳性且无UTI风险高于1%的危险因素的发热婴儿,可能无需进行尿常规或尿培养检查。

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