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阴道微生物组在妇科癌症中的作用。

The role of the vaginal microbiome in gynaecological cancer.

机构信息

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, NY, USA.

Department of Computer Science and Center for Computational Molecular Biology, Brown University, Providence, RI, USA.

出版信息

BJOG. 2018 Feb;125(3):309-315. doi: 10.1111/1471-0528.14631. Epub 2017 Apr 12.

Abstract

UNLABELLED

Human microbiome research has shown commensal bacteria to be a major factor in both wellness and disease pathogenesis. Interest in the microbiome has recently expanded beyond the gut to include a multitude of other organ systems for which the microbiome may have health implications. Here, we review the role of the vaginal microbiome in health and disease, with a particular focus on gynaecologic malignancies. Further, we suggest that it may be possible to expand the use of probiotics in the treatment of gynaecological cancers.

TWEETABLE ABSTRACT

A review of the research to date on the relation between the vaginal microbiome and gynaecological cancers.

摘要

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人类微生物组研究表明,共生细菌是健康和疾病发病机制的主要因素。人们对微生物组的兴趣最近已经从肠道扩展到包括许多其他可能对健康有影响的器官系统。在这里,我们回顾了阴道微生物组在健康和疾病中的作用,特别关注妇科恶性肿瘤。此外,我们认为有可能扩大益生菌在妇科癌症治疗中的应用。

推文摘要

对迄今为止关于阴道微生物组与妇科癌症之间关系的研究进行综述。

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