Osgood Greg M, Thawait Gaurav K, Hafezi-Nejad Nima, Shakoor Delaram, Shaner Adam, Yorkston John, Zbijewski Wojciech B, Siewerdsen Jeffrey H, Demehri Shadpour
1 Department of Orthopedics, Johns Hopkins Hospital, Baltimore, MD, USA.
2 Department of Radiology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.
Br J Radiol. 2017 May;90(1073):20160539. doi: 10.1259/bjr.20160539. Epub 2017 Mar 10.
To evaluate image quality and interobserver reliability of a novel cone-beam CT (CBCT) scanner in comparison with plain radiography for assessment of fracture healing in the presence of metal hardware.
In this prospective institutional review board-approved Health Insurance Portability and Accountability Act of 1996-complaint study, written informed consent was obtained from 27 patients (10 females and 17 males; mean age 44 years, age range 21-83 years) with either upper or lower extremity fractures, and with metal hardware, who underwent CBCT scans and had a clinical radiograph of the affected part. Images were assessed by two independent observers for quality and interobserver reliability for seven visualization tasks. Visual grading characteristic (VGC) curve analysis determined the differences in image quality between CBCT and plain radiography. Interobserver agreement was calculated using Pearson's correlation coefficient.
VGC results displayed preference of CBCT images to plain radiographs in terms of visualizing (1) cortical and (2) trabecular bones; (3) fracture line; (4) callus formation; (5) bridging ossification; and (6) screw thread-bone interface and its inferiority to plain radiograph in the visualization of (7) large metallic side plate contour with strong interobserver correlation (p-value < 0.05), except for visualizing large metallic side plate contour.
For evaluation of fracture healing in the presence of metal hardware, CBCT image quality is preferable to plain radiograph for all visualization tasks, except for large metallic side plate contours. Advances in knowledge: CBCT has the potential to be a good diagnostic alternative to plain radiographs in evaluation of fracture healing in the presence of metal hardware.
评估一种新型锥形束CT(CBCT)扫描仪在存在金属内固定物时用于评估骨折愈合情况的图像质量及观察者间的可靠性,并与普通X线摄影进行比较。
在这项经机构审查委员会批准的前瞻性研究中,符合1996年《健康保险流通与责任法案》要求,我们从27例上肢或下肢骨折且带有金属内固定物的患者(10名女性和17名男性;平均年龄44岁,年龄范围21 - 83岁)处获得了书面知情同意。这些患者接受了CBCT扫描,并对患部进行了临床X线摄影。两名独立观察者对图像进行了七个可视化任务的质量评估及观察者间可靠性评估。视觉分级特征(VGC)曲线分析确定了CBCT与普通X线摄影在图像质量上的差异。使用Pearson相关系数计算观察者间的一致性。
VGC结果显示,在可视化(1)皮质骨和(2)小梁骨;(3)骨折线;(4)骨痂形成;(5)骨桥形成;以及(6)螺纹 - 骨界面方面,CBCT图像优于普通X线片,而在可视化(7)大金属侧板轮廓方面不如普通X线片,观察者间相关性较强(p值<0.05),除了可视化大金属侧板轮廓。
对于存在金属内固定物时的骨折愈合评估,除了大金属侧板轮廓外,CBCT图像质量在所有可视化任务中均优于普通X线片。知识进展:在存在金属内固定物时评估骨折愈合方面,CBCT有潜力成为普通X线片的良好诊断替代方法。