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越南北方省份一家三级转诊医院在一年期间收治的所有新生儿的病因特异性发病率和死亡率以及转诊模式。

The cause-specific morbidity and mortality, and referral patterns of all neonates admitted to a tertiary referral hospital in the northern provinces of Vietnam over a one year period.

作者信息

Miles Merinda, Dung Khu Thi Khanh, Ha Le Thi, Liem Nguyen Thanh, Ha Khu, Hunt Rod W, Mulholland Kim, Morgan Chris, Russell Fiona M

机构信息

Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.

National Hospital of Pediatrics, Hanoi, Vietnam.

出版信息

PLoS One. 2017 Mar 10;12(3):e0173407. doi: 10.1371/journal.pone.0173407. eCollection 2017.

Abstract

OBJECTIVE

To describe the cause-specific morbidity and mortality, and referral patterns of all neonates admitted to a tertiary referral hospital in the northern provinces of Vietnam.

DESIGN

A prospective hospital based observational study.

SETTING

The Neonatal Department, National Hospital of Pediatrics, Hanoi, Vietnam.

PATIENTS

All admissions to the Neonatal Department over a 12 month period.

MAIN OUTCOME MEASURES

Cause-specific morbidity and mortality; deaths.

RESULTS

There were 5064 admissions with the commonest discharge diagnoses being infection (32%) and prematurity (29%). The case fatality ratio (CFR) was 13.9% (n = 703). Infection (38%), cardio/respiratory disorders (27%), congenital abnormalities (20%) and neurological conditions (10%) were the main causes of death. Of all the deaths, 38% had an admission weight ≥2500g. Higher CFR were associated with lower admission weights. Very few deaths (3%) occurred in the first 24 hours of life. Most referrals and deaths came from Hanoi and neighbouring provincial hospitals, with few from the most distant provinces. Two distant referral provinces had the highest CFR.

CONCLUSIONS

The CFR was high and few deaths occurred in neonates <24 hours old. The high rates of infection call for an improvement in infection control practices and peripartum antibiotic use at provincial and tertiary level. Understanding provincial hospital capacity and referral pathways is crucial to improving the outcomes at tertiary centres. A quality of care audit tool would enable more targeted interventions and monitoring of health outcomes.

摘要

目的

描述越南北方省份一家三级转诊医院收治的所有新生儿的病因特异性发病率和死亡率以及转诊模式。

设计

一项基于医院的前瞻性观察性研究。

地点

越南河内国家儿科医院新生儿科。

患者

12个月期间新生儿科收治的所有患者。

主要观察指标

病因特异性发病率和死亡率;死亡情况。

结果

共收治5064例患者,最常见的出院诊断为感染(32%)和早产(29%)。病死率(CFR)为13.9%(n = 703)。感染(38%)、心脏/呼吸系统疾病(27%)、先天性异常(20%)和神经系统疾病(10%)是主要死因。在所有死亡病例中,38%的入院体重≥2500g。较高的病死率与较低的入院体重相关。出生后24小时内死亡的病例很少(3%)。大多数转诊和死亡病例来自河内及周边省级医院,来自最偏远省份的很少。两个偏远转诊省份的病死率最高。

结论

病死率较高,24小时内新生儿死亡病例较少。感染率高要求在省级和三级医疗机构改善感染控制措施和围产期抗生素使用情况。了解省级医院的能力和转诊途径对于改善三级中心的治疗效果至关重要。护理质量审计工具将有助于进行更有针对性的干预和健康结局监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d852/5345801/fa62410882b5/pone.0173407.g001.jpg

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