子宫肌瘤在T2加权磁共振成像上的缩放信号强度作为子宫肌瘤栓塞术潜在反应的预测指标
Scaled Signal Intensity of Uterine Fibroids on T2-Weighted MR Imaging as a Predictor of the Potential Response to Uterine Fibroid Embolization.
作者信息
Kang Seung Hun, Lee Shin Jae, Jeon Gyeong Sik, Yoon Sang-Wook
机构信息
Department of Diagnostic Radiology, CHA Bundang Medical Center, CHA University, 351 Yatap-dong, Bundang-gu, Seongnam-si, Gyeonggi-do 463712, Republic of Korea.
Department of Diagnostic Radiology, CHA Bundang Medical Center, CHA University, 351 Yatap-dong, Bundang-gu, Seongnam-si, Gyeonggi-do 463712, Republic of Korea.
出版信息
J Vasc Interv Radiol. 2017 Jun;28(6):844-849. doi: 10.1016/j.jvir.2017.02.003. Epub 2017 Mar 11.
PURPOSE
To determine feasibility of scaled signal intensity (SSI) of uterine fibroids on T2-weighted magnetic resonance (MR) images to predict volume reduction rate (VRR) after uterine fibroid embolization (UFE).
MATERIALS AND METHODS
In this retrospective study, 66 premenopausal women underwent UFE. Patients underwent follow-up MR imaging 3 months after UFE. SSI of predominant fibroids was measured on T2-weighted MR images obtained before the procedure by standardizing the mean signal intensity to a 0-to-100 scale, with 0 representing rectus abdominis muscle and 100 representing subcutaneous fat (100) for reference values.
RESULTS
VRR of predominant fibroids was 12.3%-99.0% (mean 53.7%). SSI of predominant fibroids was 0.9-73.6 (mean 24.6). SSI was significantly related to VRR of fibroids (P < .01). The optimal SSI cutoff value to predict VRR > 50% was 18.16 with sensitivity of 78.8% and specificity of 66.7%. The optimal SSI cutoff value to predict VRR < 30% was 14.38 with sensitivity of 75% and specificity of 70.7%.
CONCLUSIONS
SSI of fibroids was significantly related to fibroid VRR after UFE. SSI may be useful in the quantified prediction of volume reduction.
目的
确定子宫肌瘤在T2加权磁共振（MR）图像上的缩放信号强度（SSI）预测子宫肌瘤栓塞术（UFE）后体积缩小率（VRR）的可行性。
材料与方法
在这项回顾性研究中，66名绝经前女性接受了UFE。患者在UFE后3个月接受随访MR成像。通过将平均信号强度标准化为0至100的比例来测量术前获得的T2加权MR图像上主要肌瘤的SSI，其中0代表腹直肌，100代表皮下脂肪（100）作为参考值。
结果
主要肌瘤的VRR为12.3%至99.0%（平均53.7%）。主要肌瘤的SSI为0.9至73.6（平均24.6）。SSI与肌瘤的VRR显著相关（P <.01）。预测VRR>50%的最佳SSI临界值为18.16，敏感性为78.8%，特异性为66.7%。预测VRR<30%的最佳SSI临界值为14.38，敏感性为75%，特异性为70.7%。
结论
肌瘤的SSI与UFE后肌瘤的VRR显著相关。SSI可能有助于体积缩小的定量预测。
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