Mayo Clinic in Arizona, Phoenix, AZ 85054, USA.
Mayo Clinic in Arizona, Phoenix, AZ 85054, USA.
Cancer Cell. 2017 Mar 13;31(3):305-307. doi: 10.1016/j.ccell.2017.02.011.
In this issue of Cancer Cell, Li et al. and Seckinger et al. describe promising results of two T-cell-dependent bi-specific antibodies for the treatment of multiple myeloma: one targets FcRH5 expressed on B cells, whereas the other targets the B cell maturation antigen expressed on plasma cells.
在本期《癌细胞》中,Li 等人和 Seckinger 等人描述了两种用于治疗多发性骨髓瘤的 T 细胞依赖性双特异性抗体的有希望的结果:一种针对表达在 B 细胞上的 FcRH5,另一种针对表达在浆细胞上的 B 细胞成熟抗原。