Suppr超能文献

[同种异体移植搭桥术在下肢重建中的作用]

[Role of the homograft bypass in extremity inferior's reconstructions].

作者信息

Nagy Zsuzsa, Oláh Zoltán, Kókai Judit, Molnár Anna Barbara, Laczkó Ágnes, Szabó Gábor Viktor, Juhász Viktória, Garbaisz Dávid, Berczeli Márton, Sztupinszky Zsófia, Szeberin Zoltán

机构信息

Városmajori Szív- és Érgyógyászati Klinika, Semmelweis Egyetem 1122 Budapest, Városmajor utca 68.

出版信息

Magy Seb. 2017 Mar;70(1):5-12. doi: 10.1556/1046.70.2017.1.1.

Abstract

INTRODUCTION

Vascular homografts are used for limb salvage in cases of graft infection after previous reconstructive vascular surgery or inadequate autologous veins. During multi-organ donation the thoracic aorta segment, aortic bifurcation, iliac arteries, femoral arteries, popliteal arteries, femoral veins and greater saphenous veins can be harvested. Our aim was to optimize the use of homografts by analyzing the results of previous procedures.

METHODS

The patient information was processed retrospectively, using the clinical computer system. 162 procedures were performed on 144 patients between 2007 and 2014. The short- and long-term patency, hemorrhagic complication rate, amputation rate and mortality was examined in our study. The location, graft type and length of cryopreservation were taken into consideration. Aortoiliac and femoropopliteal reconstructions with arterial and venous homografts were examined.

RESULTS

The mean age of the patients was 63.6 ± 10.7 years, the mean follow-up period was 36 ± 28 months. The primary patency rates at the postoperative 1, 3 and 6 months were 83.7%, 75.0% and 63.4%. In this study the arterial and deep venous homografts had better primary patency rates compared to the superficial venous homografts: at the postoperative 1, 3, 6 months the arterial homograft results were 85.6%, 78.6% and 74.3%, the greater saphenous vein homograft results were 81.4%, 70.4% and 47.7% in the same intervals.

CONCLUSION

The reconstructive surgical procedures in septic area mean serious challenge for the vascular surgeons. The AB0 compatibility of the graft and the recipient did not result better long-term outcomes compared to the non-compatible grafts. According to our data the ideal choice of homogenous graft is an arterial homograft which was not cryopreserved longer than 6 months.

摘要

引言

血管同种异体移植物用于先前重建性血管手术后移植物感染或自体静脉不足的肢体挽救情况。在多器官捐献过程中,可以获取胸主动脉段、主动脉分叉、髂动脉、股动脉、腘动脉、股静脉和大隐静脉。我们的目的是通过分析先前手术的结果来优化同种异体移植物的使用。

方法

使用临床计算机系统对患者信息进行回顾性处理。2007年至2014年间对144例患者进行了162例手术。我们研究了短期和长期通畅率、出血并发症发生率、截肢率和死亡率。考虑了移植物的位置、类型和冷冻保存时间。对使用动脉和静脉同种异体移植物进行的主-髂动脉和股-腘动脉重建进行了研究。

结果

患者的平均年龄为63.6±10.7岁,平均随访期为36±28个月。术后1、3和6个月的初始通畅率分别为83.7%、75.0%和63.4%。在本研究中,与浅表静脉同种异体移植物相比,动脉和深静脉同种异体移植物的初始通畅率更高:在术后1、3、6个月,动脉同种异体移植物的结果分别为85.6%、78.6%和74.3%,同期大隐静脉同种异体移植物的结果分别为81.4%、70.4%和47.7%。

结论

在感染区域进行重建性外科手术对血管外科医生来说是严峻的挑战。移植物与受体的AB0相容性与不相容移植物相比,并未带来更好的长期结果。根据我们的数据,同种异体移植物的理想选择是冷冻保存时间不超过6个月的动脉同种异体移植物。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验