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早期染色体丢失导致的微小镶嵌现象。

Minute mosaics caused by early chromosome loss.

作者信息

Ferrús A, García-Bellido A

机构信息

Facultad de Ciencias. UAM, Centro de Biología Molecular CSIC, Madrid-34, Spain.

出版信息

Wilehm Roux Arch Dev Biol. 1977 Dec;183(4):337-349. doi: 10.1007/BF00848462.

Abstract

Two genetic operations have been combined in order to ascertain whether there are differential proliferation rates in the syncytial nuclei and the blastoderm cells prior to the formation of the imaginal disc anlagen. Early chromosome loss caused by the mutantca has been associated with the generation ofMinute (M/M ) genotypes in normal (M /M ) zygotes or of non-Minute genotypes inMinute zygotes. The results indicate that there is no growth competition betweenMinute and non-Minute cells prior to the formation of the imaginal discs. Growth competition, however, leads later, during the proliferation phase of the discs, to the demarcation of compartment boundaries within imaginal discs.

摘要

为了确定在成虫盘原基形成之前,合胞体细胞核和囊胚层细胞的增殖速率是否存在差异,我们将两种遗传操作结合起来。由突变体ca引起的早期染色体丢失与正常(M /M )合子中Minute(M/M )基因型的产生或Minute合子中非Minute基因型的产生有关。结果表明,在成虫盘形成之前,Minute细胞和非Minute细胞之间不存在生长竞争。然而,生长竞争在成虫盘增殖阶段后期导致成虫盘内区室边界的划分。

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