放线菌酮对烟草天蛾细胞系中细胞伸长的影响。

Effects of cycloheximide on cellular elongation in aManduca sexta cell line.

作者信息

Oberlander H, Leach C E, Lynn D E

机构信息

Insect Attractants, Behavior and Basic Biology Research Laboratory, Agricultural Research, Science and Education Administration, USDA, 32604, Gainesville, Florida, USA.

Department of Entomology, University of Florida, 32611, Gainesville, Florida, USA.

出版信息

Wilehm Roux Arch Dev Biol. 1981 Jan;190(1):60-61. doi: 10.1007/BF00868706.

DOI:10.1007/BF00868706

PMID:28305373

Abstract

A clone (GV1) of the CHIManduca sexta cell line responds to 20-hydroxy-ecdysone by changing cellular shape from an epithelial-like form to an elongated fibroblast-like form. We have determined that this morphological response to hormone is prevented by treatment with cycloheximide. The inhibition of the elongation response by cycloheximide may relate to a requirement for the synthesis of specific proteins that play a role in the formation of cytoskeletal structure.

摘要

烟草天蛾细胞系的一个克隆（GV1）会通过将细胞形状从上皮样形态转变为细长的成纤维细胞样形态来对20-羟基蜕皮激素作出反应。我们已经确定，用环己酰亚胺处理可阻止这种对激素的形态学反应。环己酰亚胺对伸长反应的抑制可能与合成在细胞骨架结构形成中起作用的特定蛋白质的需求有关。