Zattoni Fabio, Ficarra Vincenzo, Novara Giacomo
Academic Medical Centre Hospital Santa Maria della Misericordia, Udine - Italy.
Department of Experimental and Clinic Medical Sciences, Urology Unit, University of Udine, Udine - Italy.
Urologia. 2017 Aug 1;84(3):153-157. doi: 10.5301/uro.5000220. Epub 2017 Mar 18.
Benign prostatic hyperplasia (BPH) represents an important public health problem in ageing men due to frequently associated lower urinary tract symptoms (LUTS), which may impair quality of life. BPH is also a progressive disease, mainly characterized by a worsening of LUTS over time, and in some patients by the occurrence of serious outcomes such as acute urinary retention and need for BPH-related surgery. The management of BPH and LUTS in men should move forward its focus on symptom control only. Indeed, the goals of therapy for BPH are not only to improve bothersome LUTS but also to identify those patients at risk of unfavourable outcomes in order to optimize their management and reduce complications. Risk stratification and tailored treatment should improve the reductions in both symptoms and the long-term consequences of BPH and BPH treatments. To do this, clinicians need to know possible factors that may support the develop of PBH and possible risks due to the BPH itself.
良性前列腺增生(BPH)是老年男性的一个重要公共卫生问题,因为它常伴有下尿路症状(LUTS),这可能会损害生活质量。BPH也是一种进行性疾病,主要特征是随着时间推移LUTS会恶化,在一些患者中还会出现严重后果,如急性尿潴留以及需要进行与BPH相关的手术。男性BPH和LUTS的管理不应仅局限于症状控制。实际上,BPH的治疗目标不仅是改善令人困扰的LUTS,还要识别那些有不良结局风险的患者,以便优化管理并减少并发症。风险分层和个体化治疗应能更好地减轻症状以及BPH及其治疗的长期后果。为此,临床医生需要了解可能促使BPH发生的因素以及BPH本身可能带来的风险。