Min Hyung Jun, Lee Jeong Min, Han Jung Kyu, Kim Yu Jin
*Department of Plastic and Reconstructive Surgery, Gachon University Gil Medical Center, Incheon †Department of Plastic Surgery, Korea University Guro Hospital, Seoul, South Korea.
J Craniofac Surg. 2017 Jun;28(4):e369-e372. doi: 10.1097/SCS.0000000000003687.
An epidermal cyst is one of the most common benign tumors of the skin and its major treatment method is excision. Surgical excision is treatment of choice for epidermal cysts, but the cyst wall may be ruptured during operation, especially when the cyst wall is relatively thin. The incomplete excision of the cyst sometimes occurs because of a rupture of the cyst and incomplete excision may cause recurrence. The purpose of this study is to evaluate the factors that can influence the thickness of the cyst wall of epidermal cysts.
From December 2008 to November 2013, medical records and tissue pathology slides of 290 patients with an epidermal cyst were reviewed retrospectively. The relationships among the regions, history of infection, the age of patients, and the thickness of the cyst and epidermis were analyzed.
There was no difference between thickness of cyst wall and site of occurrence and between thickness of epidermis and site of occurrence. The thickness of epidermal cyst wall with previous infection is thicker than those without infection episode (P = 0.01). However, the difference of thickness of epidermis above the cyst between with and without previous infection is not statistically significant (P = 0.641). The thickness of cyst wall and epidermis showed positive correlation (Pearson correlation coefficient 0.391, P = 0.01).
From this study, there was a tendency cyst wall with the history of infection or incision and drainage is thicker. When surgical excision, more attention to excise epidermal cyst completely is needed for the prevention of recurrence of the cyst.
表皮样囊肿是皮肤最常见的良性肿瘤之一，其主要治疗方法是切除。手术切除是表皮样囊肿的首选治疗方法，但囊肿壁在手术过程中可能破裂，尤其是当囊肿壁相对较薄时。由于囊肿破裂，有时会发生囊肿切除不完全的情况，而不完全切除可能导致复发。本研究的目的是评估可能影响表皮样囊肿囊肿壁厚度的因素。
回顾性分析2008年12月至2013年11月期间290例表皮样囊肿患者的病历和组织病理学切片。分析囊肿部位、感染史、患者年龄以及囊肿和表皮厚度之间的关系。
囊肿壁厚度与发生部位之间以及表皮厚度与发生部位之间均无差异。有既往感染的表皮样囊肿壁厚度比无感染史的厚（P = 0.01）。然而，既往有感染与无感染的囊肿上方表皮厚度差异无统计学意义（P = 0.641）。囊肿壁厚度与表皮厚度呈正相关（Pearson相关系数0.391，P = 0.01）。
本研究表明，有感染或切开引流史的囊肿壁有增厚的趋势。手术切除时，为预防囊肿复发，需要更加注意完整切除表皮样囊肿。
