Raggi Paolo, O'Neill W Charles
Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.
Department of Medicine, Division of Nephrology, Emory University, Atlanta, Georgia.
Semin Dial. 2017 Jul;30(4):347-352. doi: 10.1111/sdi.12596. Epub 2017 Mar 22.
Chronic decline in renal function is accompanied by deterioration of bone structure and function and progressive calcification of the vascular system. Both disease states have been linked with increased morbidity and mortality in chronic kidney disease. The severe alterations of mineral metabolism inherent with loss of renal function have an impact on vascular calcification development and progression, and several investigators have focused on ways to reduce their impact on vascular health. Imaging has contributed an important role in the assessment of vascular calcification, and the impact of various interventions aimed at curbing their progression.
肾功能的慢性衰退伴随着骨结构和功能的恶化以及血管系统的渐进性钙化。这两种疾病状态都与慢性肾病患者发病率和死亡率的增加有关。肾功能丧失所固有的矿物质代谢严重改变会影响血管钙化的发生和发展,一些研究人员专注于减少其对血管健康影响的方法。影像学在评估血管钙化以及各种旨在遏制其进展的干预措施的影响方面发挥了重要作用。