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肥胖症手术候选者中饮食心理病理学与阻塞性睡眠呼吸暂停之间的关系:一项回顾性研究。

The relationship between eating psychopathology and obstructive sleep apnea in bariatric surgery candidates: A retrospective study.

作者信息

Sockalingam Sanjeev, Tehrani Hedieh, Taube-Schiff Marlene, Van Exan Jessica, Santiago Vincent, Hawa Raed

机构信息

Centre for Mental Health, University Health Network, Department of Psychiatry, University of Toronto.

Toronto Western Hospital, Bariatric Surgery Program, University Health Network, Toronto, Ontario, Canada.

出版信息

Int J Eat Disord. 2017 Jul;50(7):801-807. doi: 10.1002/eat.22701. Epub 2017 Mar 23.

Abstract

OBJECTIVE

Obstructive sleep apnea (OSA), eating psychopathology, and major depressive disorder (MDD) are highly prevalent in patients with severe obesity. Our study aimed to identify differences in binge-eating disorder (BED) prevalence in bariatric surgery candidates with and without OSA.

METHODS

In this retrospective study, demographic data, psychiatric diagnoses, OSA diagnosis, binge eating, depressive and quality of life (QOL) symptoms were collected from 1,099 bariatric surgery candidates from a Canadian setting. Analysis of variance was used to identify differences in psychopathology and QOL between groups with OSA and BED, BED alone, OSA alone or neither BED or OSA.

RESULTS

Study participants' mean body mass index was 49.3 kg/m and 52.6% had a diagnosis of OSA. Patients with OSA were significantly more likely to have a diagnosis of past BED (χ  = 6.848, p = .009) and current MDD (χ  = 5.165, p = .023). Binge-eating (p < .001) and depressive symptoms (p < .001) were significantly higher in patients with co-morbid BED and OSA compared to patients with OSA alone or patients with no diagnosis of BED or OSA. Patients with co-morbid BED and OSA only had significantly lower physical (p < .001) and mental QOL (p = .007) compared to patients with no diagnosis of BED or OSA.

DISCUSSION

Our findings suggest that patients with a history of BED should be reassessed for OSA. Research is needed to examine whether BED may predispose individuals to developing obesity and OSA.

摘要

目的

阻塞性睡眠呼吸暂停(OSA)、饮食精神病理学和重度抑郁症(MDD)在重度肥胖患者中极为普遍。我们的研究旨在确定患有和未患有OSA的减肥手术候选人中暴饮暴食症(BED)患病率的差异。

方法

在这项回顾性研究中,收集了来自加拿大的1099名减肥手术候选人的人口统计学数据、精神科诊断、OSA诊断、暴饮暴食、抑郁和生活质量(QOL)症状。采用方差分析来确定患有OSA和BED、仅患有BED、仅患有OSA或既无BED也无OSA的组之间精神病理学和QOL的差异。

结果

研究参与者的平均体重指数为49.3kg/m²,52.6%的人被诊断为OSA。患有OSA的患者更有可能被诊断为过去患有BED(χ² = 6.848,p = 0.009)和当前患有MDD(χ² = 5.165,p = 0.023)。与仅患有OSA或未被诊断为BED或OSA的患者相比,合并患有BED和OSA的患者的暴饮暴食症状(p < 0.001)和抑郁症状(p < 0.001)明显更高。与未被诊断为BED或OSA的患者相比,合并患有BED和OSA的患者的身体(p < 0.001)和精神生活质量(p = 0.007)明显更低。

讨论

我们的研究结果表明,有BED病史的患者应重新评估是否患有OSA。需要进行研究以检查BED是否可能使个体易患肥胖症和OSA。

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