Bhargava Rashi, Mathur Madhu, Patodia Jyoti
Department of Pediatrics, Mahatma Gandhi Medical College and Hospital, Sitapura, Jaipur, India.
J Perinat Med. 2018 Feb 23;46(2):191-195. doi: 10.1515/jpm-2016-0373.
To study the normal oxygen saturation trends and fetomaternal correlates in healthy term newborns within 30 min of life born by normal vaginal delivery (NVD) and elective cesarean section (CS).
A cross-sectional study was conducted on 200 healthy term newborns born by NVD and elective CS at a tertiary care centre. Routine care as per the Neonatal Resuscitation Program (NRP) 2015 (Wyckoff MH, Aziz K, Escobedo MB, Kapadia VS, Kattwinkel J, Perlman JM, et al. Part 13: neonatal resuscitation: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2015;132:S543-60) protocol was given and pre-ductal arterial oxygen saturation was assessed by pulse oximetry at different intervals after birth.
The mean peripheral oxygen saturation (SpO2) was 85.4%, 90.8%, 94.1%, 95.7%, 96.7% and 97.4% at 5, 10, 15, 20, 25 and 30 min, respectively, after birth. Higher mean SpO2 was observed in NVD compared to elective CS (P<0.005). The mean time for SpO2 to reach >90% was 9.13 min in NVD and 12.31 min in elective CS (P<0.001). Maternal hemoglobin (Hb) (r=-0.15; P<0.01), birth weight (r=-0.125; P<0.05) and Apgar at 10 min (r=0.33; P<0.001) were significantly correlated with SpO2 of newborns at 10 min of life.
Our study defines normal SpO2 levels in healthy term newborns in the first 30 min of life born by NVD and elective CS. Babies born by NVD had significantly higher SpO2 levels and attained SpO2 >90% faster than those born by elective CS. Maternal Hb, birth weight and Apgar at 10 min were significant factors affecting SpO2 levels of newborns at 10 min of life.
研究经正常阴道分娩（NVD）和择期剖宫产（CS）出生的足月健康新生儿出生后30分钟内的正常血氧饱和度趋势及母婴相关因素。
在一家三级医疗中心对200例经NVD和择期CS出生的足月健康新生儿进行了一项横断面研究。按照2015年新生儿复苏计划（NRP）（Wyckoff MH、Aziz K、Escobedo MB、Kapadia VS、Kattwinkel J、Perlman JM等人。第13部分：新生儿复苏：2015年美国心脏协会心肺复苏和急诊心血管护理指南更新。《循环》。2015年；132:S543 - 60）方案给予常规护理，并在出生后的不同时间间隔通过脉搏血氧饱和度测定法评估导管前动脉血氧饱和度。
出生后5、10、15、20、25和30分钟时，平均外周血氧饱和度（SpO2）分别为85.4%、90.8%、94.1%、95.7%、96.7%和97.4%。与择期CS相比，NVD出生的新生儿平均SpO2更高（P<0.005）。NVD出生的新生儿SpO2达到>90%的平均时间为9.13分钟，择期CS出生的新生儿为12.31分钟（P<0.001）。母亲血红蛋白（Hb）（r = -0.15；P<0.01）、出生体重（r = -0.125；P<0.05）和10分钟时的阿氏评分（r = 0.33；P<0.001）与出生后10分钟时新生儿的SpO2显著相关。
我们的研究确定了经NVD和择期CS出生的足月健康新生儿出生后30分钟内的正常SpO2水平。NVD出生的婴儿SpO2水平显著更高，且比择期CS出生的婴儿更快达到SpO2>90%。母亲Hb、出生体重和10分钟时的阿氏评分是影响出生后10分钟时新生儿SpO2水平的重要因素。
