异基因造血细胞移植患者的血流细菌感染：持续宿敌的新考虑因素。
Bacterial bloodstream infections in the allogeneic hematopoietic cell transplant patient: new considerations for a persistent nemesis.
机构信息
Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Medical Center, Cincinnati, OH, USA.
Host Defense Program, Infectious Diseases, Nationwide Children's Hospital, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA.
出版信息
Bone Marrow Transplant. 2017 Aug;52(8):1091-1106. doi: 10.1038/bmt.2017.14. Epub 2017 Mar 27.
Bacterial bloodstream infections (BSI) cause significant transplant-related morbidity and mortality following allogeneic hematopoietic cell transplantation (allo-HCT). This manuscript reviews the risk factors for and the bacterial pathogens causing BSIs in allo-HCT recipients in the contemporary transplant period. In addition, it offers insight into emerging resistant pathogens and reviews clinical management considerations to treat and strategies to prevent BSIs in allo-HCT patients.
细菌性血流感染（BSI）在异基因造血细胞移植（allo-HCT）后会导致严重的移植相关发病率和死亡率。本文回顾了当代移植期 allo-HCT 受者发生 BSI 的危险因素和细菌病原体。此外，本文还深入探讨了新兴的耐药病原体，并综述了 allo-HCT 患者治疗 BSI 的临床管理注意事项和预防策略。
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