Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, 1011 North University Avenue, Ann Arbor, MI, 48109-1078, USA.
Clin Oral Investig. 2018 Jan;22(1):245-254. doi: 10.1007/s00784-017-2105-3. Epub 2017 Mar 28.
Certain Schneiderian membrane thicknesses (SMT) have shown to be more prone to tearing/perforation, and some pathologies might influence SMT. Henceforth, we aimed at studying the correlation of inflammatory status to SMT in human fresh cadaver heads.
A total of 14 fresh cadaver heads including 27 Schneiderian membrane specimens were histologically collected. A 10-item inflammatory score was determined in the entire sample and also in the thinner and thicker areas of each sample. Data was analyzed by using the Wilcoxon rank test and the Spearman's rank correlation.
The mean measured SMT was 0.40 ± 0.12 mm and the median was 0.33 ± 0.12 mm. A weak positive correlation was found between the mean SMT and inflammation score without a statistical significance. (r = 0.385, p = 0.115). The Wilcoxon signed-rank test showed a statistical difference between the medians of the thinner and thicker areas (p < 0.001). The mean inflammation score of the thinner and thicker areas was 8.55 ± 2.57 and 11.61 ± 2.65, respectively. A moderate positive and statistically significant correlation was found between the inflammation score and the thickness of the thinner and thicker areas (r = 0.638, p = 0.000).
A moderate association between the Schneiderian membrane thickness and the level of inflammation exists.
某些嗅黏膜厚度(SMT)更容易撕裂/穿孔,某些病理可能会影响 SMT。因此,我们旨在研究人类新鲜尸头中炎症状态与 SMT 的相关性。
共收集了 14 个新鲜尸头,包括 27 个嗅黏膜标本。对整个样本以及每个样本较薄和较厚区域分别进行了 10 项炎症评分。使用 Wilcoxon 秩检验和 Spearman 秩相关分析对数据进行分析。
平均测量的 SMT 为 0.40±0.12mm,中位数为 0.33±0.12mm。平均 SMT 与炎症评分之间存在弱正相关,但无统计学意义。(r=0.385,p=0.115)。Wilcoxon 符号秩检验显示较薄和较厚区域的中位数之间存在统计学差异(p<0.001)。较薄和较厚区域的平均炎症评分为 8.55±2.57 和 11.61±2.65。炎症评分与较薄和较厚区域的厚度之间存在中度正相关且具有统计学意义(r=0.638,p=0.000)。
嗅黏膜厚度与炎症水平之间存在中度相关性。