Goff J S
Department of Medicine, University of Colorado Health Sciences Center, Denver 80262.
Annu Rev Med. 1988;39:163-9. doi: 10.1146/annurev.me.39.020188.001115.
In recent years there has been an increasing awareness of infections in the esophagus and their potential to cause considerable morbidity and mortality in both normal subjects and immunocompromised patients. It is important to be cognizant of the pathogens involved, because their treatment is quite different from noninfectious esophagitis, and because inadequate treatment can lead to local complications in the esophagus or to dissemination of the infectious agent, especially in the immunocompromised host. Also, the esophagus is a site where opportunistic infections may present as one of the manifestations of the acquired immune deficiency syndrome (AIDS).
近年来,人们越来越意识到食管感染及其在正常人和免疫功能低下患者中导致相当高发病率和死亡率的可能性。认识到所涉及的病原体很重要,因为它们的治疗与非感染性食管炎有很大不同,而且治疗不当会导致食管局部并发症或感染因子播散,特别是在免疫功能低下的宿主中。此外,食管是机会性感染可能作为获得性免疫缺陷综合征(AIDS)表现之一出现的部位。