胸腔镜辅助治疗细胞毒性化疗药物胸腔外渗。
Video-assisted thoracoscopy in the management of intrapleural extravasation of cytotoxic chemotherapy.
机构信息
Cardiothoracic Surgical Unit, Department of Cardiothoracic Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
出版信息
Thorac Cancer. 2017 Jul;8(4):363-364. doi: 10.1111/1759-7714.12430. Epub 2017 Mar 31.
Abstract
The extravasation of cytotoxic agents into subcutaneous tissue is a serious complication of chemotherapy. Unfortunately, if such extravasation occurs into the pleural space, limited data is available to guide appropriate management. We present the first report in the literature of video-assisted thoracoscopy combined with a topoisomerase II inhibitor and iron chelator, dexrazoxane, in the successful management of this complication.
摘要
细胞毒药物渗出到皮下组织是化疗的严重并发症。不幸的是，如果这种外渗发生在胸膜腔，可用的数据有限，无法指导适当的治疗。我们首次在文献中报告了使用胸腔镜联合拓扑异构酶 II 抑制剂和铁螯合剂右雷佐生成功治疗这种并发症。
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