光动力疗法对大疱性类天疱疮患者的光化性角化病和基底细胞癌治疗有效。
Photodynamic therapy effective for the treatment of actinic keratosis and basal cell carcinoma in bullous pemphigoid patients.
作者信息
Canavan Theresa N, de la Feld Salma Faghri, Huang Conway, Sami Naveed
机构信息
Department of Dermatology, University of Alabama at Birmingham, United States.
Department of Dermatology, Emory University, United States.
出版信息
Photodiagnosis Photodyn Ther. 2017 Jun;18:257-259. doi: 10.1016/j.pdpdt.2017.03.019. Epub 2017 Apr 1.
Treating skin cancers and extensive actinic keratosis in patients with bullous pemphigoid (BP) can be challenging. Treatment options pose unique risks in these patients as surgical wounds can have delayed wound healing and photodynamic therapy (PDT) may exacerbate their blistering disease. We report the successful use of PDT to treat actinic keratosis and skin cancers in two patients with BP, both of whom had excellent response to PDT and tolerated treatment without any bullous disease flares. Carefully selected patients with skin cancers and stable, well controlled BP can be safely considered for treatment using PDT.
治疗大疱性类天疱疮（BP）患者的皮肤癌和广泛性光化性角化病可能具有挑战性。在这些患者中，治疗选择存在独特风险，因为手术伤口愈合可能延迟，而光动力疗法（PDT）可能会加重其水疱性疾病。我们报告了成功使用PDT治疗两名BP患者的光化性角化病和皮肤癌的案例，这两名患者对PDT均有良好反应，且耐受治疗，未出现任何水疱性疾病发作。经过仔细挑选的患有皮肤癌且BP病情稳定、控制良好的患者可以安全地考虑使用PDT进行治疗。
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