Elliott Philip H
Campbell Soup. Company, Campbell Research and Development, Campbell Place, Camden, New Jersey 08103, USA.
J Food Prot. 1996 Dec;59(13):48-53. doi: 10.4315/0362-028X-59.13.48.
While both predictive microbiology and hazard analysis critical control point (HACCP) programs are still in the developmental stages as food-safety tools, predictive models are available that are potentially useful in the development and maintenance of HACCP systems. When conducting a HACCP study, models can be used to assess the risk (probability) and determine the consequence of a microbiological hazard in food. The risk of a hazard is reduced and controlled within the HACCP framework by assigning critical control points (CCPs) to the food process. By using predictive models, ranges and combinations of process parameters can be established as critical limits for CCPs. This has the advantage of providing more processing options while maintaining a degree of safety equivalent to that of a single set of critical limits. Validation testing of individual CCPs can be reduced if the CCP models were developed with a similar food type. Microbiological as well as mechanical and human reliability models may be used to establish sets of rules for rule-based expert computer systems in an effort to automate the development of HACCP plans and evaluate the status of process deviations. Models can also be used in combination with sensors and microprocessors for real-time process control. Since HACCP is a risk-reduction tool, then predictive microbiological models are tools used to aid in the decision-making processes of risk assessment and in describing process parameters necessary to achieve an acceptable level of risk.
虽然预测微生物学和危害分析关键控制点(HACCP)计划作为食品安全工具仍处于发展阶段,但已有一些预测模型,它们在HACCP系统的开发和维护中可能会有用。在进行HACCP研究时,模型可用于评估风险(概率)并确定食品中微生物危害的后果。通过为食品加工过程指定关键控制点(CCP),可在HACCP框架内降低并控制危害风险。利用预测模型,可确定过程参数的范围和组合作为CCP的关键限值。这样做的优点是在保持与单一关键限值相当的安全程度的同时,提供更多加工选择。如果CCP模型是针对类似食品类型开发的,则可减少对单个CCP的验证测试。微生物模型以及机械和人员可靠性模型可用于为基于规则的专家计算机系统建立规则集,以便自动化HACCP计划的制定并评估过程偏差的状态。模型还可与传感器和微处理器结合用于实时过程控制。由于HACCP是一种降低风险的工具,因此预测微生物模型是用于辅助风险评估决策过程以及描述实现可接受风险水平所需过程参数的工具。